Publications by authors named "G B Pajno"
Background: Pollen allergy poses a significant health and economic burden in Europe. Disease patterns are relatively homogeneous within Central and Northern European countries. However, no study broadly assessed the features of seasonal allergic rhinitis (SAR) across different Southern European countries with a standardized approach.
View Article and Find Full Text PDFVitulia questionnaire: a new instrument to evaluate quality of life in children aged 4-7 years with food allergy.
Eur Ann Allergy Clin Immunol
July 2024
Food allergy (FA) negatively affects health-related quality of life (HR-QoL) of children and caregivers. To date, no questionnaire self-compiling assessing the HR-QoL in pre-school children with FA is available. The aim of this study is to develop and validate a self-administered, rapid and easy questionnaire to evaluate the HR-QoL in children ≥ 7 years with IgE-mediated FA.
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- There is currently no consensus on how to define and categorize the severity of food allergies, despite the existence of various scoring systems for anaphylactic reactions.
- The aim of this study was to develop a global scoring system, called DEFASE, that comprehensively assesses food allergy severity using input from international experts.
- The results showed strong agreement among experts on key components of the DEFASE score through a structured survey, marking it as the first comprehensive grading that considers the overall disease spectrum, not just individual reactions.
Article Synopsis
- Food allergies impact about 2-4% of both children and adults, prompting a guideline from the Global Allergy and Asthma European Network (GALEN) to help manage these allergies.
- A multidisciplinary international Task Force used established frameworks to review 161 studies and developed recommendations focusing on the balance of benefits and harms in managing food allergies.
- Key suggestions include avoiding known allergens, using hypoallergenic formulas for infants with cow’s milk allergy, and considering oral immunotherapy for certain allergies, while highlighting the need for further research on various treatment strategies and their effectiveness.
Currently, there are a few detailed guidelines on the overall management of children and adolescents with moderate-severe atopic dermatitis. AD is a complex disease presenting with different clinical phenotypes, which require an individualized and multidisciplinary approach. Therefore, appropriate interaction between primary care pediatricians, pediatric allergists, and pediatric dermatologists is crucial to finding the best management strategy.
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