The authors conducted histological, immunohistochemical, and morphometric studies of 47 endomyocardial biopsies and 33 hearts with a high morphological criterion for the diagnosis of arrhythmogenic right ventricular dysplasia after F.I. Marcus et al.
View Article and Find Full Text PDFHearts of 21 died patients with ischemic heart disease (IHD) have been studied by histlological and morphometrical methods. The atrial auricles derived after operation of 66 patients with heart diseases and IHD have been researched by automatic semiquantitative and immunohistochemical techniques. In general atrial fibrillation (AF) has been evident in chronic myocarditis probably conditioned by viral infections.
View Article and Find Full Text PDFThe quality of the clinical and postmortem diagnosis of renal cancer was studied, by examining 510 cases of nephrectomies and resections of the kidney for its masses over 10 years. The clinical diagnosis of the stage of renal cell carcinoma (RCC) from the data available in the inpatients records cannot be considered qualitative in 76% of cases. Joint material cutting by a surgeon and a pathologist is the most important predictor that significantly affects the quality of lifetime clinical diagnosis of the TNM stage of renal cancer.
View Article and Find Full Text PDFThe Cox multivariate regression analysis of survival rates in patients with non-metastatic clear-cell renal cell carcinoma, by taking into account both various clinical, anatomic, morphometric, and biomolecular factors and kariometric parameters, has revealed that Ki-67 and p53 expression rates along with histologic grade, a tumor portion made up of clear-cell components, and the presence/absence of tumor invasion into paranephral fat tissue are independent prognostic predictors of the disease. By applying the proposed three prognostic models (algorithms) using Ki-67 and p53 expression rates for predicting the corrected survival rates for patients with non-metastatic clear-cell renal cell carcinoma, the authors suggest that a combined biomolecular-morphometric model is of the greatest prognostic value.
View Article and Find Full Text PDFThe paper describes the history of the Saint Petersburg Society of pathologists since it was founded in 1909. It shows what great role is played by outstanding Russian medical scientists who have established their own schools of pathomorphologists and are respected in our and foreign countries. The activities of the society's members in research developments in cardiovascular and infectious diseases, cancer morphology, etc.
View Article and Find Full Text PDF