Publications by authors named "G B Haber"
Objective: To develop, externally validate, and test a series of computer algorithms to accurately predict antibiotic susceptibility test (AST) results at the time of clinical diagnosis, up to 3 days before standard urine culture results become available, with the goal of improving antibiotic stewardship and patient outcomes.
Patients And Methods: Machine learning algorithms were developed and trained to predict susceptibility or resistance using over 4.7 million discrete AST classifications from urine cultures in a cohort of adult patients from outpatient and inpatient settings from 2012 to 2022.
Objectives: To assess whether the effect of sarcopenia on neoadjuvant chemotherapy (NAC) toxicity is modified by borderline renal function (estimated glomerular filtration rate [eGFR] 40-65 mL/min) and whether sarcopenia and borderline renal function are independently associated with NAC toxicity risk.
Patients And Methods: All patients with muscle-invasive bladder cancer (MIBC) who underwent radical cystectomy (RC) between 2010 and 2022, with available cross-sectional imaging prior to NAC initiation, were included. Skeletal mass was measured from axial computed tomography images obtained at the level of the L3 vertebral body, using Aquarius Intuition software.
Article Synopsis
- - The paper presents a new type of low-cost optical structure designed for detecting magnetic fields, using an innovative magneto-plasmonic device for optical switching.
- - It features a unique setup with a 1D gold grating and a cobalt layer that enhances the switching effect, influenced by transverse magnetic fields.
- - The design allows for differential measurements between different light diffraction orders, improving sensitivity and reducing errors associated with drift and disturbances in measurements.
Objective: To compare surgical parameters and short-term outcomes between open radical cystectomy (ORC) and robotic radical cystectomy with total intracorporeal urinary diversion (icRARC).
Methods: Among the study period, 133 patients who underwent ORC and pelvic node dissection for bladder cancer (group 1) were matched and compared to 61 patients who underwent icRARC during the same period (group 2). The groups were matched 1:1 according to their propensity scores adjusted on their baseline demographics and disease characteristics.
Article Synopsis
- The study investigates the effects of prolonged ischaemia during partial nephrectomy (PN) on kidney function, highlighting a lack of research in this area despite its clinical importance.
- Among 1371 patients, the analysis focused on 759 who had assessments on kidney function pre- and post-surgery, looking at recovery rates related to ischaemia type and duration.
- Findings revealed that while warm ischaemia showed a significant negative impact on kidney recovery after 30 minutes, cold ischaemia maintained higher recovery rates, suggesting the need to limit warm ischaemia duration for better patient outcomes.