The Role of the Peyronie's Disease Questionnaire in Translation, Cultural Adaptation, and Treatment Management for Portuguese-Speaking Populations.

Peyronie's disease (PD) is characterized by the formation of fibrotic plaques within the penile connective tissue, leading to abnormal curvature, pain, and erectile dysfunction, profoundly affecting patients' physical and psychological well-being. The Peyronie's Disease Questionnaire (PDQ) is a validated instrument designed to assess key aspects of the disease, including pain, sexual function, and psychosocial impact. This narrative review underscores the importance of translating and culturally adapting the PDQ into Portuguese to enhance its applicability for Portuguese-speaking populations.

Appetite and childhood malnutrition: A narrative review identifying evidence gaps between clinical practice and research.

Severe Acute Malnutrition (SAM) is a critical global health issue, contributing to approximately one-half of all child mortality worldwide. SAM management guidelines recommend the use of appetite assessment determined by an "appetite test" to distinguish between complicated and uncomplicated SAM, subsequently guiding clinical decisions regarding outpatient versus inpatient care and discharge from hospital. Despite the widespread utilization of this recommendation, its validity lacks substantial evidence within the existing literature.

Urinary arsenic species and birth outcomes in Tacna, Peru, 2019: a prospective cohort study.

Arsenic exposure during pregnancy might affect foetal development. Arsenic metabolism may modulate the potential damage to the fetus. Tacna has the highest arsenic exposure levels in Peru.

Systemic biological mechanisms underpin poor post-discharge growth among severely wasted children with HIV.

In sub-Saharan Africa, children with severe malnutrition (SM) and HIV have substantially worse outcomes than children with SM alone, facing higher mortality risk and impaired nutritional recovery post-hospitalisation. Biological mechanisms underpinning this risk remain incompletely understood. This case-control study nested within the CHAIN cohort in Kenya, Uganda, Malawi, and Burkina Faso examined effect of HIV on six months post-discharge growth among children with SM and those at risk of malnutrition, assessed proteomic signatures associated with HIV in these children, and investigated how these systemic processes impact post-discharge growth in children with SM.