[Study of beta-lactamase activity of staphylococci from different sources].

The beta-lactamase activity of staphylococci isolated from the nasopharynx and skin of children with destructive affections of the lungs and from blood of patients with cardiovascular diseases subjected to surgical operations was determined with acidometric and microbiological procedures. Interrelation between synthesis of beta-lactamase by the staphylococcal strains and their resistance to beta-lactam antibiotics was demonstrated. No correlation of the antibiotic resistance and the taxonomic position of the staphylococcal strains was observed.

[Variability of the pathogenicity traits of populations of staphylococci in a surgical hospital].

The results of the study of heterogeneity of staphylococcal populations at a surgical ward are presented. The study deals with qualitative and quantitative characteristics of three groups of pathogenicity factors: protease (the penetration factor), protein A (the function of protection from phagocytosis) and alpha-hemolysin (the toxic function). The study shows that the greatest number of S.

[Use of coulometric titration for elucidating the mechanism of the oxidation of 6-APA alkaline breakdown products by halogens].

Penaldinic acid and penicillamine were formed on alkali decomposition (1 N NaOH) of 6-APA for 20 minutes at room temperature, penicillamine being completely oxidized to disulphide by the air oxygen. Coulometric titration of the alkali decomposition products showed that generated chlorine in 0.5 N HCl solution or bromine in a week acid solution of KBr oxidized them with participation of 7 electrones.