Publications by authors named "G Aygencel"

Article Synopsis
  • This study investigates the link between sepsis-induced acute kidney injury (AKI) and worse outcomes in patients in the intensive care unit (ICU), focusing on identifying risk factors for new-onset AKI among septic patients who initially had no kidney issues.
  • Conducted at Gazi University Hospital, the research involved analyzing data from septic patients aged 18 and older, looking at demographics and clinical factors to determine predictors of AKI development and mortality rates.
  • Results showed a significant incidence of new-onset AKI (36%), particularly linked to factors like invasive mechanical ventilation, new-onset shock, and higher APACHE-II scores, all of which correlated with longer ICU stays and increased mortality risk.*
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Objective: This study aimed to investigate the relationship between procalcitonin (PCT) kinetic and estimated glomerular filtration rates (eGFR) in critically ill patients who had Gram-negative primary bloodstream infection (GN-BSI) and responded to the antimicrobial therapy.

Materials And Methods: This single-centered study was retrospective and observational. Critically ill GN-BSI patients over 18 years old who had clinical and microbiological responses to antibiotic treatment were included in the study.

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Background: The coexistence of sepsis and hematological malignancies increases patient vulnerability, revealing the need for precise prognostic markers. This study explores the prognostic significance of lactate levels and clearance in septic patients with hematological malignancies.

Materials And Methods: A retrospective cohort study from January 2016 to December 2019 in a tertiary hematological intensive care unit (ICU) included 167 adults with hematological malignancies and sepsis.

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Article Synopsis
  • Critically ill cirrhotic patients face a high mortality risk from acute-on-chronic liver failure, and while traditional scoring systems like MELD and Child-Pugh provide some insight, they have limitations that need addressing.* -
  • A study involving 175 of these patients showed that the lactate/albumin ratio (LAR) could be a useful prognostic tool, comparable to established scores, with higher ratios linked to increased ICU mortality.* -
  • The findings suggest that LAR, alongside the SOFA score assessed at 48 hours, could help predict outcomes and inform treatment strategies, paving the way for further research to validate these results.*
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Aim: critical illness often leads to malnutrition and diaphragmatic dysfunction (DD), common in intensive care units (ICU). Ultrasonography (US) is a potent tool for detecting DD. This study examines the connection between malnutrition risk and DD in ICU patients using ultrasonographic diaphragm measurements in medical ICU patients.

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