Publications by authors named "G Avenel"
Objectives: To determine a potential window of opportunity for retreatment with rituximab in patients with rheumatoid arthritis (RA) from a multicentre longitudinal real-life study based on tight monitoring with ultrasonography (US).
Methods: Thirty RA patients treated with rituximab were included. US parameters were collected at each time (8 visits) of the 18-month follow-up, notably the global score of power Doppler (PD) activity.
Article Synopsis
- - NJBI (Native Joint and Bone Infections) can be linked to infective endocarditis (IE) in about 15% of cases, prompting this study to analyze factors that predict positive echocardiograms for IE in NJBI patients.
- - The study reviewed medical records of 546 hospitalized NJBI patients between 2007-2017 and found that 12% had echocardiograms suggestive of IE, with key factors like having 2+ positive blood cultures and high-risk cardiac conditions increasing this likelihood.
- - Researchers developed the "Normandy score," which incorporates data on cardiac health, bacterial type, and infection mechanisms to help determine when echocardiography is necessary, boasting a 100
This study aims to evaluate in patients hospitalized for vertebral osteomyelitis (VO) the effectiveness of bacteriological diagnosis and the yield of percutaneous needle biopsy (PNB) and to identify factors associated with the result of PNB. This retrospective, two-centre study was conducted between 2000 and 2009. Data on patients with VO were retrieved from the diagnosis database and confirmed by checking medical records.
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- Targeted therapies like crizotinib are commonly used to treat ALK-rearranged non-small cell lung cancer (NSCLC), but adverse effects need to be closely monitored due to rapid drug developments.
- A case involved a 31-year-old woman who developed osteitis, resembling bone metastasis, after 3 months on crizotinib, showing the importance of distinguishing between side effects and cancer progression.
- This is the first documented instance of crizotinib-induced osteitis, suggesting that its action on multiple kinases may lead to unexpected complications like extensive bone inflammation.
Objective: To determine predictive/predictable factors of relapse in rheumatoid arthritis (RA) patients undergoing biologic Disease-Modifying Anti-Rheumatic Drugs (bDMARDs) dose reduction/discontinuation.
Patients And Methods: RA patients receiving the same bDMARD for more than 1 year, in Simplified Disease Activity Index (SDAI) remission, were selected in an observational monocentric real-life study. The 18-month follow-up included spacing (6 months) and withdrawal (12 months) periods of bDMARD.