[Diagnostic blood flow changes in the outflow tract of the left ventricle. A Doppler echocardiography study of arterial hypertension].

In patients with arterial hypertension we analyzed left ventricular filling by pulsed wave (PW) Doppler in the left ventricular inflow and outflow tract (LVIT and LVOT resp.). Separately, we determined the optimal position of flow analysis within the LVOT.

Antiadrenergic effect of M-cholinoceptor stimulation on human ventricular contractility in vivo.

The relevance of an indirect negative inotropic effect of pharmacological or vagally mediated M-cholinoceptor stimulation in the human ventricle in vivo is unknown. The inotropic response induced by isoproterenol (isoprenaline, 20 ng.kg-1 x min-1), measured by m-mode echocardiography as the increase of fractional shortening in seven healthy subjects, was reduced from 17.