Publications by authors named "G Arca"

Article Synopsis
  • Perinatal mortality is notably high in low- and middle-income countries, with accurate fetal gestational age assessment essential for differentiating between prematurity and intrauterine growth restriction for better management strategies.
  • The study conducted in Barcelona sought to validate post-mortem ultrasound measurements of the cerebellum as a method for estimating gestational age in cases of fetal and perinatal deaths.
  • Findings demonstrated a strong correlation between various cerebellar measurements and gestational age, with the extrauterine transcerebellar diameter emerging as the most reliable predictor, regardless of the trimester in which the measurement was taken.
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Background: It has been suggested that a 30-50 % lithium dose reduction or lithium discontinuation 24-48 h before delivery could minimize neonatal complications. We investigated the maternal lithemia changes around delivery after a brief discontinuation, the placental transfer of lithium at delivery, and the association between neonatal lithemia at delivery and acute neonatal outcomes.

Methods: A retrospective observational cohort study was conducted in a teaching hospital (November/2006-December/2018).

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Background: Brain injury and poor neurodevelopment have been consistently reported in infants and adults born before term. These changes occur, at least in part, prenatally and are associated with intra-amniotic inflammation. The pattern of brain changes has been partially documented by magnetic resonance imaging but not by neurosonography along with amniotic fluid brain injury biomarkers.

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It is estimated that 96% of infants with hypoxic-ischaemic encephalopathy (HIE) are born in resource-limited settings with no capacity to provide the standard of care that has been established for nearly 15 years in high-resource countries, which includes therapeutic hypothermia (TH), continuous electroencephalographic monitoring and magnetic resonance imaging (MRI) in addition to close vital signs and haemodynamic monitoring. This situation does not seem to be changing; however, even with these limitations, currently available knowledge can help improve the care of HIE patients in resource-limited settings. The purpose of this systematic review was to provide, under the term "HIE Code", evidence-based recommendations for feasible care practices to optimise the care of infants with HIE and potentially help reduce the risks associated with comorbidity and improve neurodevelopmental outcomes.

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Background: Massive infarction in adults is a devastating entity characterized by signs of extreme swelling of the brain's parenchyma. We explored whether a similar entity exists in neonates, which we call massive neonatal arterial ischemic stroke (M-NAIS), and assess its potential clinical implications.

Methods: Prospective multicenter cohort study comprising 48 neonates with gestational age ≥35 weeks with middle cerebral artery (MCA) NAIS was performed.

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