Time-restricted feeding reduces inflammatory markers and downregulates JAG1 and NICD protein levels in the liver of aged mice.

Objectives: The present study aimed to assess whether Time-Restricted Feeding (TRF) modulates inflammation and hepatic Notch1 signalling in C57BL/6J-aged mice.

Methods: Adult mice submitted to the ad libitum diet, aged (24 months-old) submitted to the ad libitum diet and, aged-TRF (24 months-old) subjected to the TRF (12 hours fed in the active cycle and 12 hours fasting in the light cycle) for 8 weeks. We investigated metabolic parameters, liver histology, metabolic-dysfunction-associated fatty liver disease activity score, collagen fiber, hepatic mitochondrial respiration, and publicly available liver Rna-seq datasets from human livers in diverse clinical conditions to clarify Notch1 involvement in liver health.

Effectiveness of Child-rearing Information Booklet among Adolescent Mothers: A Quasi-experimental Non-equivalent Pre-test-Post-test Control Group Study.

Background: Child-rearing is challenging for adolescent mothers at risk of providing limited care to their children because of the challenges and demands of simultaneously being an adolescent and a mother. Children aged 0-2 years depend on caregivers like their young mothers to promote their physical, emotional, social, and cognitive growth and development.

Objective: The study aimed to determine the effectiveness of the Child-rearing Information Booklet (CRIB) among adolescent mothers with children aged 0-2 years on the three dimensions of knowledge, attitude, and practices.

Patient-Nurse Communication in an Oncology Hospital Setting: A Qualitative Study.

Background: Communication is an important aspect in making patients competent to define, process, and manage their disease condition as well as to intercept and satisfy psychosocial needs. Communication between patient and nurse is central to the learning and orientating process since the nurse has the greatest frequency and continuity of relationship with patients and their families. This study aims to investigate the quality of communication between patient and nurse and the factors that promote or hinder effective communication from the oncology patient's perspective within an inpatient hospital setting.

Engaging With New Mexico's County and Tribal Health Councils: Practical Implications From a Co-created Online Resource to Enhance Academic and Community Collaboration Toward Health Initiatives.

The Community-based Participatory Research (CBPR) model fosters equitable partnerships between communities and academic institutions to promote health equity. This model emphasizes shared control over all phases of the research process and recognizes the limited power and inequalities experienced by marginalized communities. At our institution, Community Engagement Liaison Specialists (CELS) build relationships with New Mexico communities, guided by CBPR principles.

Risky Behaviors for Non-Communicable Diseases: Italian Adolescents' Food Habits and Physical Activity.

Background: Driving adolescents to more correct food habits and physical activity is crucial to promoting health and avoiding the increase in morbidity and mortality in adulthood. Literature has focused on these behaviors in the adult population, while studies on adolescents are more limited. This study aims to explore the level of knowledge, attitudes, and behaviors regarding nutrition and physical activity to acquire insight into adolescents and identify the associated predictors.