Publications by authors named "G Antoniadis"
Nerve tumors in the retroperitoneal space are a rarity. Radical surgery according to soft tissue tumors can lead to persistent pain and neurological deficits. This study aims to evaluate clinical outcomes of patients treated by a visceral- / neurosurgical approach.
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- Plexus injuries lead to chronic issues like paralysis, sensory loss, and pain, prompting interest in how the dorsal root ganglia (DRG) are affected following such injuries.
- A study involving 13 patients revealed that in about half, the typical cell structure of DRG was lost replaced by connective tissue, while others maintained their cellular integrity, although those with preserved neurons reported less pain.
- The findings suggest two distinct patient groups: those with neuronal preservation who might benefit from anti-inflammatory treatments, and those with neuronal loss needing further research for potential regenerative therapies.
Article Synopsis
- Peripheral nerve injuries can lead to the formation of neuromas, which are abnormal growths at the injury site that can stop nerves from healing properly.
- Researchers studied human neuroma tissue and compared it to healthy nerves from the same person to understand what happens at the injury site over time (1-13 months after injury).
- They found that even though the nerve repair cells called Schwann cells were present, they were in a "repair mode" and different from healthy cells, with signs of inflammation and reduced ability to form myelin, which is important for nerve function.
Article Synopsis
- * A 30-year-old male with symptoms of meningoencephalomyelitis was treated with plasmapheresis, corticosteroids, and mycophenolate mofetil, resulting in positive recovery outcomes.
- * The case highlights the necessity of early intervention for neurourological issues, showing how specialized care can enhance patient quality of life in complex neurologic disorders.
Article Synopsis
- - The study highlights that most peripheral nerve tumors are benign, primarily consisting of schwannomas and neurofibromas, but also discusses rare tumors and non-tumorous lesions that can mimic these conditions, based on data from a German registry of 315 patients.
- - The cohort includes 61 cases of unusual tumors, showcasing a range of pathological features and biological potentials, with diagnoses like malignant peripheral nerve tumors, perineurioma, hybrid tumors, and various extrinsic lesions like lymphoma and hemangioma.
- - A definitive preoperative diagnosis is often challenging, necessitating collaboration among specialists in radiology, neurology, neuropathology, and neurosurgery to improve diagnosis and treatment options for patients.