Publications by authors named "G Amaya Villagran"
Characterization of muscle mass, strength and mobility of critically ill patients with SARS-CoV-2 pneumonia: Distribution by sex, age, days on mechanical ventilation, and muscle weakness.
Front Physiol
February 2023
Article Synopsis
- A study evaluated how sex, age, and duration of mechanical ventilation affected muscle mass, strength, and mobility in critically ill patients infected with SARS-CoV-2 in an ICU setting in Chile.* -
- It included 132 participants, demonstrating significant decreases in quadriceps muscle thickness, with notable declines in specific muscle areas during their ICU stay.* -
- Results showed that older patients and those on mechanical ventilation for more than 10 days experienced greater muscle loss and had lower muscle strength and mobility upon discharge.*
Following publication of the original article [1], an error was reported in the tagging of Joël Fokom Domgue in the author group. The tagging in this correction article has been fixed.
View Article and Find Full Text PDFBackground: A low cost and accurate method for detecting high-risk (HR) human papillomavirus (HPV) is important to permit HPV testing for cervical cancer prevention. We used a commercially available HPV method (H13, Hybribio) which was documented to function accurately in a reduced volume of cervical specimen to determine the most prevalent HPV types and the distribution of HPV infections in over 1795 cancer-free women in Guatemala undergoing primary screening for cervical cancer by cytology.
Methods: HR-HPV detection was attempted in cervical samples from 1795 cancer-free women receiving Pap smears using the Hybribio™ real-time PCR assay of 13 HR types.
Purpose: Cervical cancer is one of the most common causes of cancer mortality for women living in poverty, causing more than 28,000 deaths annually in Latin America and 266,000 worldwide. To better understand the molecular basis of the disease, we ascertained blood and tumor samples from Guatemala and Venezuela and performed genomic characterization.
Experimental Design: We performed human papillomavirus (HPV) typing and identified somatically mutated genes using exome and ultra-deep targeted sequencing with confirmation in samples from Mexico.