Publications by authors named "G Altunbas"
Article Synopsis
- Glycogen synthase kinase 3β (GSK3β) is an enzyme linked to heart failure (HF), and this study examines its serum levels in various HF types.
- Researchers analyzed serum GSK3β levels in 112 HF patients and 50 healthy controls, employing echocardiographic evaluations and statistical analyses to determine significance.
- Results indicated that GSK3β levels were significantly elevated in HF patients compared to controls, with highest levels in heart failure with preserved ejection fraction (HFpEF) and lowest in reduced ejection fraction (HFrEF), suggesting a potential protective mechanism related to ejection fraction.*
Objective: Sodium-glucose co-transporter-2 inhibitors (SGLT-2i) are a new class of drugs that lower blood glucose and reduce mortality in heart failure patients with reduced ejection fraction (HFrEF). They also have antioxidant effects. The exact mechanism of SGLT-2i is unknown.
View Article and Find Full Text PDFObjective: In this study, we measured the levels of Kelch-like ECH-associated protein 1 (KEAP1), which has the potential antioxidant capacity, among non-ST elevation myocardial infarction (NSTEMI) patients compared with healthy controls. We also investigated the possible association between KEAP1 levels and the GRACE score, which is a universal risk score commonly used for patients with acute myocardial infarction.
Patients And Methods: As the patient group, 78 patients admitted to our center with a diagnosis of NSTEMI were included in the study.
Myocardial infarction is extremely rare in children. However, chest pain suspected to be cardiac in origin by the parents is a very common presenting symptom in pediatric emergency services. In this case, an electrocardiogram is very important in the differential diagnosis of cardiogenic complaints and should be carefully considered.
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