Housing RCS rats under specific pathogen-free conditions mildly ameliorates retinal degeneration and alters intestine microbiota.

Retinitis pigmentosa (RP) is a genetic blinding disease with over 80 causative genes. Disease progression varies between patients with similar genetic backgrounds. We assessed the association between environment, gut microbiota, and retinal degeneration in the RP rat model Royal College of Surgeons (RCS).

Investigating the interplay between morphosyntax and event comprehension from the perspective of intersecting object histories.

In a series of sentence-picture verification studies we contrasted, for example, "… choose the balloon with "… inflate the balloon" and "… the inflated balloon" to examine the degree to which different representational components of event representation (specifically, the different object states entailed by the inflating event; minimally, the balloon in its uninflated and inflated states) are jointly activated after state-change verbs and past participles derived from them. Experiments 1 and 2 showed that the initial and end states are both activated after state-change verbs, but that the initial state is considerably less accessible after participles. Experiment 3 showed that intensifier adverbs (e.

A novel approach to the assessment of higher-order rule learning in male mice.

Historically, the development of valid and reliable methods for assessing higher-order cognitive abilities (e.g., rule learning and transfer) has been difficult in rodent models.

Online eye tracking and real-time sentence processing: On opportunities and efficacy for capturing psycholinguistic effects of different magnitudes and diversity.

Online research methods have the potential to facilitate equitable accessibility to otherwise-expensive research resources, as well as to more diverse populations and language combinations than currently populate our studies. In psycholinguistics specifically, webcam-based eye tracking is emerging as a powerful online tool capable of capturing sentence processing effects in real time. The present paper asks whether webcam-based eye tracking provides the necessary granularity to replicate effects-crucially both large and small-that tracker-based eye tracking has shown.

Encoding and inhibition of arbitrary episodic context with abstract concepts.

Context is critical for conceptual processing, but the mechanism underpinning its encoding and reinstantiation during abstract concept processing is unclear. Context may be especially important for abstract concepts-we investigated whether episodic context is recruited differently when processing abstract compared with concrete concepts. Experiments 1 and 2 presented abstract and concrete words in arbitrary contexts at encoding (Experiment 1: red/green colored frames; Experiment 2: male/female voices).