A 'gap' between physician and patient assessment of symptom severity in acute cystitis?: a multicenter trial of women treated with extended-release ciprofloxacin.

The current trial assessed differences in physician and patient symptom-severity perceptions in ambulatory outpatient females with uncomplicated urinary tract infections (uUTIs). We also investigated the efficacy and safety profile of once-daily ciprofloxacin in a 500-mg PO extended-release formulation for 3 days to treat acute cystitis. This prospective, open-label, multicenter (1,972 sites), phase 4 clinical trial enrolled 7,614 adult women with a clinical diagnosis of an acute uUTI.

Educating patients with uncomplicated UTIs: the effect of an educational brochure on patient knowledge.

We evaluated the effectiveness of an educational brochure designed to increase patient knowledge about uncomplicated urinary tract infections (uUTIs). Participants were adult female outpatients (average age, 45 years) with a clinical diagnosis of uUTI. The 1,972 study sites (primary care physicians' offices and urology clinics) were randomized to receive patient enrollment kits with or without educational brochures.