Publications by authors named "G Alcoba"
Article Synopsis
- Febrile illnesses that persist despite initial treatment are a common issue in low-resource subtropical settings, often caused by infectious diseases that are neglected and have limited diagnostic options.
- A systematic review was conducted across 196 articles from various countries in Africa, Asia, and Central/South America, focusing on "prolonged fevers" in adults and children while excluding well-known diseases like malaria and TB.
- Among the neglected diseases identified, rickettsioses and relapsing fever borreliosis were the most common causes reported, particularly in Eastern Africa, along with other diseases such as brucellosis and leishmaniasis.
Background: Snakebite clinical trials have often used heterogeneous outcome measures and there is an urgent need for standardisation.
Method: A globally representative group of key stakeholders came together to reach consensus on a globally relevant set of core outcome measurements. Outcome domains and outcome measurement instruments were identified through searching the literature and a systematic review of snakebite clinical trials.
Vulnerability to snakebite envenoming and access to healthcare in the Terai region of Nepal: a geospatial analysis.
Lancet Reg Health Southeast Asia
February 2023
Article Synopsis
- Snakebite envenoming is a neglected tropical disease impacting poor rural populations, highlighting the need for timely treatment and improved resource allocation as per the WHO's roadmap.
- A study conducted in Nepal's Terai region analyzed risk distribution and travel accessibility, finding that 2.07 million rural residents face high vulnerability primarily due to neurotoxic snakebite syndrome.
- Results suggest that by optimizing treatment capacity across health facilities, coverage in rural areas could significantly increase from about 66% to nearly 94%, potentially benefiting over 3.8 million people.
Snakebite clinical trials have often used heterogeneous outcome measures and there is an urgent need for standardisation. A globally representative group of key stakeholders came together to reach consensus on a globally relevant set of core outcome measurements. Outcome domains and outcome measurement instruments were identified through searching the literature and a systematic review of snakebite clinical trials.
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