Publications by authors named "G Accarino"

Background: Arterial diseases like coronary artery disease, carotid stenosis, peripheral artery disease, and abdominal aortic aneurysm have high morbidity and mortality, making them key research areas. Their multifactorial nature complicates patient treatment and prevention. Biomarkers offer insights into the biochemical and molecular processes, while social factors also significantly impact patients' health and quality of life.

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Background: The AFX unibody endograft offers advantages in treating abdominal aortic aneurysms (AAAs) with narrow aortic bifurcations due to its unique design, where the flow divider sits at the native aortic bifurcation. However, its limited length options may limit complete proximal neck utilization. As per device instruction for use, the implant should be completed with an aortic cuff.

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Introduction: To confirm real-world clinical practice results reported with anatomically fixed bifurcated endograft, a physician-initiated study was designed-AFX2-LIVE registry.

Materials And Methods: From November 2019 to August 2021, investigators enrolled all consecutive patients treated with AFX2 (Endologix Inc., Irvine, CA, USA) endograft.

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Article Synopsis
  • A study was conducted to evaluate the performance of the Endurant stent graft in treating abdominal aortic aneurysms (AAAs) over a medium and long-term period, including patients treated both within and outside the device's instructions for use (IFU).
  • The research involved 795 patients over 14 years, comparing two groups: those treated according to IFU guidelines and those who were not, noting significant differences in aneurysm neck characteristics and outcomes between the groups.
  • Results showed a low aneurysm-related mortality rate (<1%) and a 10.5% endoleak rate, with larger AAAs and shorter prosthesis necks correlating with increased risks of complications and reintervention.
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Background: Microplastics and nanoplastics (MNPs) are emerging as a potential risk factor for cardiovascular disease in preclinical studies. Direct evidence that this risk extends to humans is lacking.

Methods: We conducted a prospective, multicenter, observational study involving patients who were undergoing carotid endarterectomy for asymptomatic carotid artery disease.

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