Outcome of venom bradykinin potentiating factor on rennin-angiotensin system in irradiated rats.

Purpose: The objective of this work was to compare the effect of a bradykinin potentiating (BPF) isolated from venom of Egyptian scorpion Androctonus amoreuxi as a natural angiotensin converting enzyme inhibitor (ACEI) with losartan (LOS), a chemical angiotensin receptor blocker (ARB), in the modulation of radiation-induced damage.

Material And Methods: Rats were grouped into: (i)

Control: untreated; (ii) + C(BPF): Received intraperitoneally (i.p.

Fractionation and characterization of Cerastes cerastes cerastes snake venom and the antitumor action of its lethal and non-lethal fractions.

In the present study fractionation of the Cerastes cerastes cerastes snake venom by gel filtration on Sephadex G-75 gave 14 protein fractions. Phospholipase PLA2 activity is not uniformly correlated with the lethality to mice in regard to all venom fractions. F11 which is the richest in PLA2 activity is less toxic than F3, which contains a small amount of PLA2, and F12 is the lowest in lethality and PLA2 activity.

Some pharmacological studies on the effects of Cerastes vipera (Sahara sand viper) snake venom.

The effects of the venom of the Sahara sand viper (Cerastes vipera) were studied on isolated chick biventer cervicis, isolated rat atria and vas deferens preparations, and on the electrocardiogram of anaesthetized rats. Effects on 3H-noradrenaline uptake were studied using rat brain synaptosomes. At 50 micrograms/ml and 100 micrograms/ml, the venom caused a transient increase in rate and force of contractions of the rat atria followed by an irreversible depression.

The effect of the viper Cerastes cerastes cerastes venom and venom fractions on carbohydrate metabolism.

The effect of the viper Cerastes cerastes cerastes venom and venom fractions on carbohydrate metabolism. Toxicon 31, 791-801, 1993.--I.

Alleviation of the heat load on lactating goats with the use of diuretics and drinking cool water.

The effect was studied of different heat loads connected with the application of diuretics and of 10 to 15 degrees C drinking water on the milk production and some related physiological parameters of 19 Egyptian Baladi goats under experimental conditions. The increase in heat stress increased the respiration rate, rectal temperature, and serum prolactin concentration significantly, while it significantly decreased the milk production, the content of alkaline, and acid phosphatases creatinine, urea, red blood cells, and haemoglobin concentration. The diuretic Thiameterine and cool drinking water under hot conditions improved the milk yield and had a positive effect on the physiological status of the animals, especially their blood composition.