The relation between ABO blood groups, HLA typing and giardiasis in children.

A total of 455 children were chosen randomly and surveyed for giardiasis by stool examination using several techniques. A case control study design was adopted where 91 cases of giardiasis (symptomatic and asymptomatic) and 101 children giardiasis free were examined. ABO blood groups and HLA typing were investigated.

Some immunological studies on amoebiasis.

Studies of immunoglobulins pattern in 64 patients with different clinical symptoms of amoebiasis revealed that IgG showed no rise in patients with acute amoebic dysentery and asymptomatic cyst passers, while it was significantly increased in patients with active hepatic amoebiasis. IgM, IgA and IgE were significantly increased in both acute amoebic dysentery and active hepatic amoebiasis, but no significant changes in asymptomatic cyst passers. ELISA (depended on level of IgG) was valid and reliable in diagnosis of active hepatic amoebiasis (100%), IHAT (depended on level of IgM) gave 72.

Immunization against experimental trichinosis using T. spiralis larvae and hydatid fluid antigens.

Immunization of mice against T. spiralis infection using T. spiralis larval glycoproteins as homogenous antigen and crude hydatid fluid as heterogenous antigen showed a marked reduction in larvae burden and a significant rise of serum IgE in immunized mice infected with T.

Evaluation of adult Schistosoma mansoni and cercarial antigens in serodiagnosis of schistosomiasis using IHAT and ELISA.

Examination of 200 bilharzial cases divided into four groups and 50 normal controls to evaluate the efficiency of adult Schistosoma mansoni and cercarial antigens in serodiagnosis of schistosomiasis using IHAT and ELISA revealed that IHA test showed high sensitivity that decreased with the progress of clinical status of the disease if adult worm antigen was utilized. Also IHAT adult antigen was more sensitive for serodiagnosis than with cercarial antigen, while ELISA is less sensitive using both cercarial and adult antigens.

The effect of cyclosporin A (CSA) on murine visceral toxocariasis canis.

Swiss mice experimentally infected with T. canis were treated by Cyclosporin A (CSA). The direct antiparasitic effect was noticed when administered on the same day of infection and was more effective when repeated for eight weeks.