Publications by authors named "G A Thouas"
Background: To evaluate the safety, efficacy and tolerability of a combination micronutrient and polyherbal preparation ( ) for gout management.
Methods: A single arm, open-label pilot study was conducted at the National Hospital for Traditional Medicine in Vietnam. Participants (n=35 recruited) diagnosed with chronic gout received four tablets of daily over a 45-day period.
Electroactive materials have been investigated as next-generation neuronal tissue engineering scaffolds to enhance neuronal regeneration and functional recovery after brain injury. Graphene, an emerging neuronal scaffold material with charge transfer properties, has shown promising results for neuronal cell survival and differentiation in vitro. In this in vivo work, electrospun microfiber scaffolds coated with self-assembled colloidal graphene, were implanted into the striatum or into the subventricular zone of adult rats.
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- Low birth weight in fathers can affect their children's health, making them more likely to have heart and metabolic diseases later in life.
- This study looked at how male baby rats that were born small affect their offspring (the next generation) before the babies are even born.
- The results showed that these small-born male rats have different gene expressions and how they use nutrients, even though their offspring looked normal at first.
Low birth weight is associated with an increased risk for adult disease development with recent studies highlighting transmission to subsequent generations. However, the mechanisms and timing of programming of disease transmission to the next generation remain unknown. The aim of this study was to examine the effects of low birth weight and advanced maternal age on second-generation preimplantation blastocysts.
View Article and Find Full Text PDFStudy Question: What is the relationship between cleavage stage embryo kinetics, blastocyst metabolism and subsequent embryo viability?
Summary Answer: Embryos cleaving faster at the first cleavage division resulted in blastocysts with a larger inner cell mass (ICM), higher glucose consumption, lower glycolytic rate, higher aspartate uptake, lower global amino acid turnover and higher percentage of developing fetuses on E13.5 when compared with blastocysts that developed from slower cleaving embryos.
What Is Known Already: Previous research has shown that morphokinetics, blastocyst carbohydrate metabolism and cleavage stage amino acid metabolism of the preimplantation embryo can be used independently as markers of its developmental competence and subsequent viability.