Impairment of the blood-nerve and blood-brain barriers in apolipoprotein e knockout mice.

Apolipoprotein E (apoE) is well characterized as a plasma lipoprotein involved in lipid and cholesterol metabolism. Recent studies implicating apoE in Alzheimer's disease and successful recovery from neurological injury have stimulated much interest in the functions of apoE within the brain. To explore the functions of apoE within the nervous system, we examined apoE knockout (KO) mice.

[A method of concentrating viruses in environmental water sources].

The authors propose an effective and simple method for the collection and concentration of enteroviruses from environmental water bodies, which is based on adsorption properties of macroporous glass (MPG). MPG enveloped in water-permeable coating permits concentration directly in the water. Poliomyelitis viruses were 100-1000-fold concentrated in laboratory trials.

Electropherotypes and serotypes of human rotavirus in Estonia in 1989-1992.

The electropherotypes and serotypes of human rotaviruses circulating in Tallinn (Estonia) in 1989-1992 have been studied. Rotaviruses were found in 372 (25.8%) of 1,442 faecal specimens of pediatric patients with acute diarrhea.

Inactivation of simian rotavirus SA 11 by hydrogen peroxide.

The kinetics and extent of the simian rotavirus SA 11 (RV) inactivation by low concentrations of hydrogen peroxide (HP) were determined. The curves illustrating the kinetics of crude virus inactivation have "tailing off". The inactivation of the purified virus runs according to the first-order kinetics.