Experimental model of resection craniotomy with subsequent reconstruction of the defect with a polymer implant enables comprehensive assessment of functional and ultrastructural changes during replacement of the damaged tissue. Reconstruction of a skull defect was accompanied by transient motor disturbance in the acute period and did not cause functional disorders and neurological deficits in a delayed period. Histological examination of osteal and brain tissue revealed no pathological reactions that could be associated with the response to the chemical components of the implant.
View Article and Find Full Text PDFThe article presents a high-productivity laser-structuring method combined with a hydrophobic post-treatment to create zone-structured surfaces with a decreasing wetting angle on AISI 304 stainless steel surfaces. We have investigated the impact of laser processing modes and hydrophobic substances on wetting and hysteresis angles and successfully demonstrated autonomous droplet movement over this zone-structured surface. A critical condition for autonomous fluid flow is the need for the drop to touch the boundary between the two zones.
View Article and Find Full Text PDFAccurate color reproduction is highly important in multiple industrial, biomedical and scientific applications. Versatile and tunable light sources with high color-rendering quality are very much in demand. In this study, we demonstrate the feasibility of multi-wavelength Bragg diffraction of light for this task.
View Article and Find Full Text PDFThe pharmacological induction and activation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α), a key regulator of ischemic brain tolerance, is a promising direction in neuroprotective therapy. Pharmacological agents with known abilities to modulate cerebral PGC-1α are scarce. This study focused on the potential PGC-1α-modulating activity of Mexidol (2-ethyl-6-methyl-3-hydroxypyridine succinate) and Semax (ACTH analog) in a rat model of photochemical-induced thrombosis (PT) in the prefrontal cortex.
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