[Inflammatory markers in Alzheimer's disease and vascular dementia].

The following markers of inflammation: enzymatic activity of leukocyte elastase (LE), functional activity of alpha-1-proteinase inhibitor (α1-PI), levels of C-reactive protein (CRP) and interleukin-6 (IL-6) were measured in the blood plasma of patients with Alzheimer's disease (AD) and vascular dementia (VD). The results confirm the presence of an inflammatory component in the pathogenesis of AD and VD. The high level of CRP may be considered as a marker of VD in the early stages of disease.

[Cholinergic therapy of Alzheimer's disease and its effect on health and quality of life of caregivers to the patients].

To assess efficacy and safety of 4-month therapy with rivastigmine in Alzheimer's disease (AD) and to evaluate the burden of caregivers to these patients, 25 AD patients have been studied. Rivastigmine was prescribed internally and 22 patients were assigned to additional antipsychotic therapy at the admission to the hospital. The treatment duration was 16 weeks (12 weeks in the hospital and 4 weeks after the discharge).

[Obtaining transgenic Solanum tuberosum potato plants with active bacterial genes xyl and T-cyt effecting the phytohormone balance].

The genetic constructions based on integrative vector pGV3850 were used to introduce bacterial genes xyl and T-cyt into potato cells. The transformation was carried out using the leaf-disc method with modifications. A special system for obtaining regenerants from explants of potato in vitro plants or calli has been designed that permitted the selection of transgenic shoots.