Publications by authors named "G A Pollock"
The burden of medical contraindications to corneal donation: Time for review.
PLOS Glob Public Health
December 2024
Corneal graft (keratoplasty) is the most common allograft in the world, but the imbalance between the number of donors and the number of patients waiting for transplants is abysmal on a global scale and varies enormously from one country to another. The risk of transmission of systemic diseases from donor to recipient is demonstrably low. In over 50 years and an estimated 2.
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- The rise of sequence type (ST) 45 methicillin-resistant Staphylococcus aureus (MRSA) has been notable in the past decade, but its causes are not fully understood.
- Research involving phylogenetic analysis of ST45 MRSA from Australia and globally identified a unique lineage with multidrug resistance, particularly in Australia and Singapore.
- The study found that the qacA gene, acquired in the late 1990s, enhances tolerance to chlorhexidine, indicating that both antimicrobial resistance and qacA are key to the establishment of ST45 MRSA.
Background: There has been high uptake of rapid antigen test device use for point-of-care COVID-19 diagnosis. Individuals who are symptomatic but test negative on COVID-19 rapid antigen test devices might have a different respiratory viral infection. We aimed to detect and sequence non-SARS-CoV-2 respiratory viruses from rapid antigen test devices, which could assist in the characterisation and surveillance of circulating respiratory viruses in the community.
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- * Rates of antimicrobial resistance are rising, posing an urgent threat, as identified by the CDC, highlighting the need for effective vaccines against these infections.
- * The review discusses existing vaccine research, including past clinical trials and new antigen identification methods, and outlines future research priorities for vaccine development to combat infections.
Article Synopsis
- * Long-term data from clinical trials is still awaited, but there is optimism surrounding the effectiveness of gene therapy for sickle cell disease.
- * There is concern regarding the financial burden of gene therapy on patients, especially in low-resource settings, emphasizing the need to find solutions to mitigate these costs.