Publications by authors named "G A Poland"
Objectives: We estimated vaccine effectiveness (VE) against SARS-CoV-2 infection among a statewide cohort of people with HIV (PWH) and compared the estimates with a matched cohort of people without HIV (PWoH) in South Carolina (SC), USA.
Methods: A population-based cohort was retrieved from statewide electronic health records between January 2, 2021, and April 14, 2022, during which several variants were circulating in SC (i.e.
Article Synopsis
- - Older adults (65+) often have weaker responses to flu vaccines, leading to the recommendation of special vaccines like MF59-adjuvanted (MF59Flu) and high-dose (HDFlu) vaccines for this age group in the U.S.
- - A study analyzed gene expression in CD4 T cells from 234 older vaccine recipients before and after vaccination, finding numerous differentially expressed genes (DEGs) that varied between MF59Flu and HDFlu recipients.
- - Interestingly, the identified DEGs did not significantly correlate with immune responses against the flu virus, indicating that other factors might be at play when it comes to flu immunity in older adults.