Publications by authors named "G A Parikh"
Article Synopsis
- This study examined the impact of corticosteroids on headache pain in patients with spontaneous subarachnoid hemorrhage (SAH), aiming to determine if short-term use could alleviate refractory pain despite limited evidence supporting this treatment.
- A total of 213 patients were analyzed, with findings indicating that those treated with corticosteroids experienced a modest reduction in maximum daily pain scores on days 1-3 post-treatment, particularly on day 3, while mean daily pain scores and opioid consumption were not significantly affected.
- The research employed advanced statistical methods, including propensity score matching and inverse probability treatment weighting, to ensure balanced comparisons between patients receiving corticosteroids and those who did not, providing more reliable results regarding
Objective: Comatose survivors of cardiac arrest (CA) pose a complex challenge for physicians reliant on imperfect studies to determine the extent of neurologic injury. Clinically available imaging is frequently relied upon despite limited sensitivity. We conducted a prospective pilot study comparing diffusion kurtosis imaging (DKI)-MRI and somatosensory evoked potentials (SSEPs) in comatose survivors of CA to investigate the benefit of utilizing higher diffusion b-values to enhance prediction of arousal recovery.
View Article and Find Full Text PDFBackground: Patients with severe stroke are at high risk of secondary neurologic decline (ND) from the development of malignant cerebral edema (MCE). However, early infarcts are hard to diagnose on conventional head computed tomography (CT). We hypothesize that high-energy (190 keV) virtual monochromatic imaging (VMI) from dual-energy CT (DECT) imaging enables earlier detection of ND from MCE.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the outcomes of patients who underwent ECMO (extracorporeal membrane oxygenation) following acute neurosurgical interventions across four high-volume centers in the U.S.
- Researchers reviewed data from 24 adults who underwent various neurosurgical procedures before or during ECMO, aiming to determine survival rates and neurologic outcomes.
- Findings showed that 63% of these patients survived to hospital discharge, with 80% of those having favorable neurologic outcomes, suggesting that ECMO could be beneficial even in cases with significant neurologic injury.
Article Synopsis
- Traumatic brain injury (TBI), even mild, can lead to long-lasting symptoms and a higher risk of dementia, possibly due to problems in the brain's glymphatic system, which normally clears waste.
- This study evaluated the enlarged perivascular space (ePVS) and the ALPS index in 44 mTBI patients at two points: about 14 days and 6-12 months after injury, also comparing them to 37 control participants.
- Key results showed significant correlations where higher ePVS was linked to more memory problems shortly after injury, and an increase in the ALPS index over time was associated with better sleep, suggesting these markers may help predict recovery outcomes for TBI patients.