[Efficiency of meldonium in the complex therapy of acute coronary syndrome].

We examined 140 patients (mean age 54.8±3.1 years) with ST elevation acute coronary syndrome resulting in Q-wave myocardial infarction of the left ventricle.

[The influence of a low- and high-frequency electromagnetic fields on seeds].

It was shown that the exposure of seeds in the rest phase to a low-frequency pulse electromagnetic field leads to substantial changes in seed physiology during germination. The changes at the physiological level in sprouting seeds depend not only on the frequency of the external EMF and its power characteristics but also on the kind of seeds. Low- and high-frequency electromagnetic fields are able to produce a biostimulation effect; however, the mechanisms of its appearance are different in their nature.

[Effect of the melanostatin analogue alaptide on dopamine-dependent behavior in rats reared in isolation].

The effects of alaptide, a new analog of melanostatine, on self-stimulation of the lateral hypothalamus, rotation behavior in rotometer, and stereotypy were studied in rats bred in social isolation from other animals beginning from the 17th day of birth and rats bred in groups. Alaptide potentiated amphetamine-stimulated behavior only in rats reared in social isolation. This effect was lateralized: the left rotation dominated.

Effects of abused drugs on thresholds and breaking points of intracranial self-stimulation in rats.

The present study aimed to compare the effects of various abused drugs on threshold current intensities and the breaking points of intracranial self-stimulation. Effects of morphine (1-10 mg/kg, s.c.

Comparison of the effects of dopamine agonists on self-stimulation of the hypothalamus with lesioning of mesolimbic brain structures in rats reared in conditions of social isolation.

Initial and phenamine-stimulated frequencies of self-stimulation of the lateral hypothalamus were not significantly different in rats reared in communities and in conditions of social isolation. Unilateral lesioning of the ventral tegmental area and the medial prefrontal cortex in early ontogenesis increased phenamine sensitivity only in isolated rats. The dopamine receptor agonist apomorphine, at a dose of 0.