Publications by authors named "G A Otterson"
Article Synopsis
- * Pleural mesothelioma is the most common type, accounting for about 85% of all cases.
- * The NCCN Guidelines for Mesothelioma: Pleural provide updated recommendations on diagnosis, treatment, and follow-up, with recent revisions focusing on disease classification and systemic therapy options.
Article Synopsis
- The trial investigated the effects of adding a stereotactic body radiation therapy (SBRT) boost to the primary tumor in patients with locally advanced non-small cell lung cancer (LA-NSCLC) before undergoing standard chemoradiation treatment, aiming to improve primary tumor control rates.
- Out of 21 enrolled patients, the one-year primary tumor control rate was 100%, with promising results showing improved response rates and manageable side effects, notably a low occurrence of severe toxicities.
- Correlative studies revealed significant imaging changes and identified specific genetic markers associated with increased pulmonary toxicity, giving insight into future treatment monitoring and patient management.
What Is This Summary About?: This is a summary of the results of a study called PHAROS. This study looked at combination treatment with encorafenib (BRAFTOVI) and binimetinib (MEKTOVI). This combination of medicines was studied in people with metastatic non-small-cell lung cancer (NSCLC).
View Article and Find Full Text PDFBackground: Immune checkpoint inhibitors (ICIs) are a first-line and perioperative treatment for lung cancer. Pneumonitis is a potentially life-threatening complication of ICI treatment in 2% to 5% of patients; however, risk factors for developing ICI pneumonitis (ICI-p) remain undefined.
Methods: We conducted a retrospective cohort study of consecutive patients with lung cancer who received at least one dose of ICI from 2015 through 2020 at The Ohio State University.
Background: After George Floyd's murder in 2020, the Center for Disease Control and Prevention (CDC) called systemic racism a public health crisis. This health crisis is connected to the already-documented racial and socioeconomic disparities in cancer care. Ensuring hematologists and oncologists are aware of these disparities through their medical education can help to address these disparities.
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