Publications by authors named "G A Nixon"
Article Synopsis
- - EEG spectral analysis is a more sensitive method for assessing sleep disruption compared to traditional sleep architecture, helping to differentiate between children with narcolepsy, idiopathic hypersomnia (IH), and those with subjective sleepiness.
- - The study analyzed specific EEG frequency powers (delta, theta, alpha, sigma, and beta) during various sleep stages and found significant differences, particularly in beta and theta power levels among the groups of children tested.
- - Results showed that children with narcolepsy displayed higher theta power than those with subjective sleepiness, while delta power was lower in both narcolepsy and IH groups, suggesting unique patterns that could enhance understanding of these sleep disorders.
Article Synopsis
- The study investigates differences in sleep architecture among children with narcolepsy, idiopathic hypersomnia (IH), and those who are subjectively sleepy, aiming to improve diagnostic methods.
- It involved 28 children with narcolepsy, 11 with IH, and 26 control subjects, analyzing sleep stability and disturbance through polysomnography and multiple sleep latency tests (MSLT).
- Results showed narcoleptic children had more frequent wake transitions and shorter REM episode durations compared to the other groups, suggesting that specific sleep patterns could help differentiate between these sleep disorders in children.
Despite the availability of effective treatment and vaccines for hepatitis B virus (HBV) and C virus (HCV), many people are still infected and remain unaware of their infection. The Camden and Islington Viral Hepatitis Identification Tool (CIVHIT), a computer-based search tool, was introduced in 60 general practices (GPs) in April 2014 to support identification, testing and treatment of individuals at high risk for blood-borne viruses (BBVs). CIVHIT searched electronic medical records (EMRs), flagging all those with codes linked to risk factors or medical conditions associated with BBVs.
View Article and Find Full Text PDFA highly efficient method to synthesize diverse symmetrical phosphinic acids with the potential to act as pivotal candidates in the design of HIV-1 protease inhibitors has been developed. Such compounds have been designed based on the enzyme-substrate specificity, and their elongated analogues are expected to demonstrate significant inhibition against the HIV-1 protease with IC values in the low nanomolar range. Moreover, a highly efficient esterification protocol with carbohydrates and flavonoids has been devised to address the inherent absorption challenges associated with phosphinic-based drugs.
View Article and Find Full Text PDFTaken out of context: academic rural health in Aotearoa New Zealand.
J Prim Health Care
September 2024