Publications by authors named "G A Nikulina"

The comparative analysis of expression level of FCRL1 gene encoding human B-cell surface receptor in healthy individuals and patients with autoimmune diseases was carried out. For the expression estimation we used results of DNA dot-hybridization on the membranes, containing cDNA samples from subpopulations of blood cells of patients with autoimmune diseases. The quantitative estimation of hybridization signals showed that expression level of FCRL1 gene in peripheral blood B-lymphocytes was significantly higher in patients with a multiple sclerosis, lupus anticoagulans, Takayasu's arteritis and also in von Willebrand disease than in healthy individuals.

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The study of 70 patients with acute ischemic stroke has demonstrated that ischemic stroke is associated with central hypoacusis the symptoms of which are subjectively weak. It is suggested that development of neurosensory hypoacusis of the III-IV degree may serve a prognostic sign of a poor outcome of acute ischemic attack.

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In patients with acute pyelonephritis, the efficiency has been studied of the blood transcutaneous laser irradiation and of the medicamentous membrane-stabilizing therapy, with n = 31 and n = 27 respectively. In the serous stage of acute pyelonephritis both methods appeared to be efficient while in the transitional stage it is the membrane-stabilizing therapy that has been shown to be superior to transcutaneous blood laser irradiation.

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The space flight of physician cosmonaut V.V. Polyakov, the longest to date (438 days), has yielded new data about human adaptation to long-term weightlessness.

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