Publications by authors named "G A Mueller"

Aim: To determine if short- (2-5 days) course antimicrobials are as effective as standard- (6-14 days) course antimicrobials in the treatment of symptomatic UTI in children.

Methods: MEDLINE and EMBASE were searched from their origin to January 2024. We only considered randomised controlled trials in children <18 years of age.

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Breast cancer is the second leading cause of cancer deaths among women. Multiple microRNAs (miRNAs) have been reported to be associated with breast cancer progression or metastasis. The purpose of the current study was to identify plasma extracellular miRNAs associated with incident breast cancer.

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Background: The objective of this study was to compare the accuracy of available tests for pyuria, including newer automated tests, and to examine the implications of requiring them for the diagnosis of urinary tract infections (UTIs).

Methods: We included children between 1 and 36 months of age undergoing bladder catheterization for suspected UTIs who presented to 1 of 3 pediatric centers. Using a positive urine culture result as the reference standard, we compared the sensitivity of 5 modalities for assessing pyuria at the cutoffs most often used clinically for detecting children with a positive culture result: leukocyte esterase on a dipstick, white blood cell (WBC) count on manual microscopy with and without using a hemocytometer, automated WBC enumeration using flow cytometry, and automated WBC enumeration using digital imaging with particle recognition.

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Article Synopsis
  • The study aimed to assess how lifestyle and behavioral interventions impact body composition and anthropometric measures in individuals with spinal cord injury (SCI).
  • Researchers conducted a systematic review of 61 studies, primarily focusing on exercise interventions, including those paired with functional electrical stimulation, supplements, or educational efforts.
  • Findings suggested that exercise led to reductions in BMI and waist circumference, although there were no significant changes in total body fat or lean mass, indicating that exercise-based strategies could be effective for improving body composition in this population.
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Article Synopsis
  • - The study evaluates vaccination coverage against respiratory diseases (SARS-COV-2, influenza, and pneumococcus) in Swiss individuals with spinal cord injuries, using a survey conducted in 2022 and examining factors like demographics and health conditions.
  • - Among 1158 participants, vaccination rates were highest for SARS-COV-2 at 86.5%, followed by influenza at 44.6% and pneumococcus at just 7.5%, with doubts about vaccine effectiveness and side effects being common reasons for hesitancy.
  • - The findings reveal low vaccination rates for influenza and pneumococcus in this population, highlighting the need for better public health strategies and specific interventions to address vaccine hesitancy effectively.
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