Publications by authors named "G A Lloyd"

Article Synopsis
  • * The researchers developed a new measurement called the restitution threshold index (RTI), which reflects the burden of short R-R intervals and found it correlates with reduced LVEF and improvement in LVEF after catheter ablation (CA).
  • * In a study with 104 patients, those with reduced LVEF had a significantly higher RTI, indicating it as a strong predictor for recognizing the risk of LVEF decline and predicting recovery after CA.
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Article Synopsis
  • Atrial fibrillation-induced cardiomyopathy (AIC) is characterized by a drop in left ventricular ejection fraction (LVEF) due to AF, but the reasons why some patients develop AIC are still unclear.* -
  • The study hypothesizes that subtle heart muscle issues exist before LVEF decreases; therefore, a detailed examination of heart function following successful catheter ablation is essential to identify these features.* -
  • Results show that out of 41 participants, 82.9% recovered LVEF post-ablation, yet many still had signs of heart dysfunction, with significant portions exhibiting elevated NT-proBNP levels, ongoing heart failure symptoms, and impaired heart performance despite normalization of LVEF.*
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Background: The clinical potential of Raman spectroscopy is well established but has yet to become established in routine oncology workflows. One barrier slowing clinical adoption is a lack of evidence demonstrating that data taken on one spectrometer transfers across to data taken on another spectrometer to provide consistent diagnoses.

Methods: We investigated multi-centre transferability using human oesophageal tissue.

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Article Synopsis
  • * Current guidelines for treating asymptomatic patients focus on heart size and function, but even after surgery, there's still a risk of heart failure and death.
  • * New methods, including machine learning and advanced imaging techniques, are being developed to identify high-risk patients who might benefit from earlier interventions, with valve repair being the preferred treatment.
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Article Synopsis
  • This study aimed to enhance understanding of upper tract imaging in patients assessed for hematuria, evaluating imaging rates and effectiveness using a national cohort of insured individuals.
  • A total of 466,710 patients were analyzed between 2010 and 2015, with various imaging modalities revealing low detection rates: ultrasound (1%), CT (1.7%), and other methods (2.7%).
  • The results suggest that while the diagnostic yield of imaging is higher than expected, overall detection remains low, indicating a potential preference for using ultrasound in initial evaluations based on updated guidelines.
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