Publications by authors named "G A Lied"

Article Synopsis
  • - The study aimed to understand how different diets (higher-carbohydrate vs. low-carbohydrate) affect gastrointestinal health, symptoms, quality of life, and fecal short-chain fatty acids (SCFAs) in individuals with obesity over 12 months.
  • - Participants were divided into three dietary groups: one with refined carbs, one with minimally refined carbs, and a low-carb high-fat diet, with no significant weight loss differences observed in the long term.
  • - While fiber intake increased in all groups, there were no notable changes in irritable bowel syndrome symptoms, but significant improvements in reflux symptoms were reported in one dietary group after 12 months.
View Article and Find Full Text PDF

Purpose: Irritable bowel syndrome (IBS) is a diagnosis defined by gastrointestinal (GI) symptoms like abdominal pain and changes associated with defecation. The condition is classified as a disorder of the gut-brain interaction (DGBI), and patients with IBS commonly experience psychological distress. The present study focuses on this distress, defined from reports of fatigue, anxiety, depression, sleep disturbances, and performance on cognitive tests.

View Article and Find Full Text PDF

Background: The relationship between gut microbiota and irritable bowel syndrome (IBS) subtype is unclear. We aimed to explore whether differences in fecal bacteria composition and short-chain fatty acid (SCFA) levels were associated with subtypes and symptoms of IBS.

Methods: All participants delivered fecal samples and self-reports on IBS Symptom Severity Score (IBS-SSS), Bristol Stool Scale (BSS), and Gastrointestinal Symptom Rating Scale (GSRS).

View Article and Find Full Text PDF

Background: A low FODMAP diet (LFD) is an established dietary treatment for patients with irritable bowel syndrome (IBS). However, knowledge on the extended effects of the restriction phase regarding nutrient intake, symptom severity, and quality of life (QoL) is sparse. Therefore, our objectives were to evaluate the safety of a dietitian-led 12-week strict LFD on measures of blood biochemistry, nutritional status, symptom severity, and QoL.

View Article and Find Full Text PDF

Purpose: The diagnosis of irritable bowel syndrome (IBS) is based on symptom-based criteria due to lack of reliable disease-specific biomarkers. Gut microbiota is perturbed in IBS and when comparing different methods used to analyze gut microbiota, the results might be obscured. Therefore, in this systematic review we aimed to investigate the profile of fecal bacterial markers and dysbiosis index (DI) in patients with IBS and IBS subgroups compared to healthy controls (HCs) conducted by the same method (GA-map Dysbiosis Test based on16S rRNA sequencing).

View Article and Find Full Text PDF