SenMayo transcriptomic senescence panel highlights glial cells in the ageing mouse and human retina.

There is a growing need to better characterise senescent cells in the CNS and retina. The recently published SenMayo gene panel was developed to identify transcriptomic signatures of senescence across multiple organ systems, but the retina was not included. While other approaches have identified senescent signatures in the retina, these have largely focused on experimental models in young animals.

Ligand modulated charge transfers in Z-scheme configured Ni-MOF/g-CN nanocomposites for photocatalytic remediation of dye-polluted water.

The development of photocatalysts must be meticulous, especially when they are designed to degrade hazardous dyes that cause mutagenesis and carcinogenesis. In this meticulous approach, Ni-based metal-organic frameworks with different ligands, including terephthalic acid (NTP), 2-aminoterephthalic acid (NATP), and their composite with g-CN (NTP/GCN, and NATP/GCN) have been synthesized using hydrothermal method. Structural analysis by XRD and ATR-IR revealed synergistic properties due to robust chemical interactions between the NATP-MOFs and GCN systems.

Thoracic spinal anaesthesia - An effective alternative to general anaesthesia in breast surgeries: A randomised, non-blinded study.

Background And Aims: General anaesthesia (GA) is the preferred modality for breast surgeries; however, neuraxial anaesthesia can be performed in cases where GA poses a significant risk. We hypothesise that neuraxial blockade is a safe and effective alternative to GA in short-duration breast surgeries.

Methods: This randomised study included 30 patients of the American Society of Anesthesiologists physical status I and II, who were scheduled for elective breast surgeries of a duration of less than 90 min.

Auditory cortex encodes lipreading information through spatially distributed activity.

Watching a speaker's face improves speech perception accuracy. This benefit is enabled, in part, by implicit lipreading abilities present in the general population. While it is established that lipreading can alter the perception of a heard word, it is unknown how these visual signals are represented in the auditory system or how they interact with auditory speech representations.