Publications by authors named "G A Gutierrez-Aceves"
A Comprehensive Revision of Radiation Immunotherapy and the Abscopal Effect in Central Nervous System Metastases: Reassessing the Frontier.
Curr Issues Mol Biol
October 2024
Seventy years ago, Robin Mole introduced the concept of the abscopal effect to describe a rare phenomenon. This occurs when local radiation triggers an immune-mediated reduction in tumors outside the treated area but within the same organism. Observing this effect has been linked to improved overall and progression-free survival in patients who experience it.
View Article and Find Full Text PDFDiagnostic Algorithm for Intracranial Lesions in the Emergency Department: Effectiveness of the Relative Brain Volume and Hounsfield Unit Value Measured by Perfusion Tomography.
Cureus
June 2024
Article Synopsis
- Early treatment of intracranial lesions is crucial but challenging to differentiate, as each type requires different treatment strategies; Cerebral computed tomography perfusion (CTP) imaging is effective in visualizing and quantifying brain lesions' vascularity.
- This study evaluated the effectiveness of Hounsfield units (HU) and CTP in distinguishing various intracranial space-occupying lesions over a five-year period, involving 244 patients with conditions including glioblastomas, primary central nervous system lymphoma, metastases, and abscesses.
- Results indicated that combining rCBV and HU measurements enhances diagnostic accuracy for differentiating lesions, and the simplicity and availability of CTP make it a valuable tool for diagnosing and managing brain tumors.
Corpus callosotomy is a therapeutic approach for drug-resistant epilepsy, with positive outcomes observed in managing atonic seizures. Despite a decline in its usage, radiosurgical callosotomy remains a viable option for drug-resistant epilepsy due to its low risks of post-radiation neoplasia, albeit not with exceptions. Brain radionecrosis is characterized by tissue death and vascular endothelial damage following the procedure.
View Article and Find Full Text PDFObjective: Our primary objective is to evaluate the local control of optic nerve sheath meningiomas (ONSMs) treated with ionizing radiation and related visual changes after treatment. Our secondary objective is to describe the clinical characteristics and perform an analysis of the treatment impact on the functional status of this group of patients.
Methods: We present our series of 19 patients treated with ionizing radiation therapy at our radio-neurosurgery unit between 2016 and 2022.
Comparison of microvascular decompression, percutaneous radiofrequency rhizotomy, and stereotactic radiosurgery in the treatment of trigeminal neuralgia: A long term quasi-experimental study.
Pain Pract
March 2024
Background: Microvascular decompression (MVD), radiofrequency rhizotomy (RFR), and stereotactic radiosurgery (SRS) are surgical techniques frequently used in the treatment of idiopathic trigeminal neuralgia (TN), although the results reported for each of these are diverse.
Objective: This study aimed to compare long-term pain control obtained by MVD, SRS, and RFR in patients with idiopathic TN.
Methods: To compare the results obtained by MVD, SRS, and RFR we chose a quasi-experimental, ambispective design with control groups but no pretest.