[Specific features of endogenous autorosette formation in the peripheral blood of cancer patients].

The nature and rate of endogenous autorosette formation were investigated in peripheral blood from cancer patients. Both neutrophils, monocytes and platelets were involved. The latter lysed red blood cells.

[Study of conformation structure and molecular interactions of rosamycin by infrared spectrum analysis].

IR spectra of rosamycin and its solutions in inert (CCl4 and C2Cl4), proton acceptor (tetrahydrofuran, hexametapol and diethylamine) and proton donor (CHCl3 and CH3OD) solvents were studied at various concentrations (0.1 to 0.001 mol/l) and temperatures (20 to 100 degrees C) in the region of the vC = O and vOH absorption bands (1600-1800 and 3200 3650 sm 1).

[Infrared spectra and the molecular conformations of macrolide-group antibiotics in solution].

IR spectra (1,600-1,800, 3,100-3,700 cm-1) of tetrachlorethylene solutions of macrolide antibiotics such as erythromycin monohydrate and dihydrate, oleandomycin, erythrolose amine and anhydroerythromycin were obtained. The atoms and atomic groups included into the hydrogen bond were determined. It was shown that the antibiotic molecule conformations were stabilized by the intramolecular hydrogen bonds.

[IR spectral research on erythromycin mono- and dihydrates].

The IR spectra of crystalline and amorphous forms of erythromycin monohydrate and dihydrate were investigated and their characteristic spectral features were described. Differences in the system of the intermolecular hydrogen bonds and in the level of perfection of the crystalline structures of the monohydrate and dihydrate were detected. It was shown that both crystallohydrates of erythromycin might exist in two polymorphous modifications.