Publications by authors named "G A Gorecki"
Can combined spinal and epidural anesthesia be the gold standard for laparoscopic surgery for pregnant patients? This case report presents a first trimester pregnant patient who was admitted for obstructive jaundice syndrome (pain in the right hypochondrium, nausea, and vomiting). Initially, because of the risk/benefit ratio of pregnancy, the treatment was medical and the patient was immediately discharged because her clinical condition improved, but she was rapidly readmitted to the surgery department because of worsening symptoms. Emergency surgical intervention (laparoscopic cholecystectomy) under combined spinal and epidural anesthesia (CSEA) was performed to reduce the patient's risks.
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- Carotid endarterectomy is a procedure used to prevent strokes in patients with narrowed carotid arteries, but it can lead to serious complications like severe hypotension, which increases the risk of stroke and heart issues.
- A study of 160 patients found that 30.6% experienced severe hypotension, with common risk factors including diabetes, heart valve issues, and longer surgery times.
- The use of a temporary shunt during surgery was specifically linked to an increased likelihood of severe hypotension, suggesting that selective shunting may be beneficial for patients with additional health concerns.
Article Synopsis
- Parkinson's disease is a neurodegenerative condition that often includes psychiatric symptoms like anxiety and depression in over 60% of patients, leading to a high risk of impulse control disorders (ICDs) such as compulsive shopping and gambling.
- A study conducted over six years explored pharmacological treatments for ICDs among Parkinson's patients, using the Hamilton Rating Scale to evaluate their symptoms and outcomes.
- The results showed a reduction in impulsive behaviors among patients, and the article discusses potential future research directions to further address these symptoms.
Background/aim: Ovarian cancer remains a major cause of death in women worldwide, mainly due to late diagnosis and the lack of a reliable screening test for early detection of the disease. In this context, attention has been focused on the identification of other prognostic factors that might allow a better identification of cases with worse long-term outcome.
Patients And Methods: Data of patients who underwent cytoreductive surgery between 2014-2019 were retrospectively reviewed and 57 patients were considered eligible for this study.
Article Synopsis
- - Most high grade serous ovarian cancers (HGSOC) start in the fallopian tube and spread, prompting the need to study immune responses at different sites of the disease.
- - Research shows that tertiary lymphoid structures (TLSs) in ovarian tumors are less developed compared to those found in fallopian tube or omental tumors, affecting immune cell activity.
- - The study highlights that normal mesenchymal stem cells (nMSCs) may enhance B cell function and TLS formation, while cancer-educated mesenchymal stem cells (CA-MSCs) hinder this process, potentially limiting the positive effects of TLS on tumor prognosis.