Predictors of 7-day mortality in critically ill patients with hyperglycemic crisis : A single center retrospective analysis.

Aim/hypothesis: The main aim of the study was to identify point of care available laboratory and clinical predictors of 7‑day mortality in critically ill patients with a hyperglycemic crisis.

Methods: A retrospective study of 990 patients with the first hospitalization due to hyperglycemia was performed. Patients were classified as having diabetic ketoacidosis (DKA) or being in a hyperosmolar hyperglycemic state (HHS) according to the recommendations of the American Diabetes Association (ADA).

The Evidence Effect: How Fact Boxes Shift Perceptions of Lung Cancer Screening in Austrian Medical Practice.

Background: Recent results from the Dutch NELSON study have rekindled debates about the benefit-to-harm ratio of lung cancer screening and the comprehension of this by physicians.

Methods: This research surveyed the perception and understanding of 136 Austrian physicians regarding the advantages and risks of lung cancer screening, examining the impact of educational data visualization tools, including fact box and icon array. Physicians participated in an online survey about their understanding before and after exposure to either a fact box alone or combined with an icon array.

Comparison of whole-body 18F-FDG-PET/CT with 18F-FDG-PET/CT limited to skull base to upper abdomen for primary staging of lung cancer - a retrospective explorative analysis.

The gold standard for ruling out distant metastases as part of primary staging in lung cancer is whole-body F-FDG-PET/CT, but this method is resource-intensive. Recent evidence suggests that examining only the thorax and upper abdomen may be sufficient 1 2 3. If a limited F-FDG-PET/CT approach proves effective for proper staging, it could lead to quicker examinations and reduced radiation exposure.

Sodium-chloride difference is not strongly correlated with base excess in chronic kidney disease: an anion gap problem.

Introduction: The prevalence of metabolic acidosis is high in patients with chronic kidney disease (CKD). For the diagnosis, a blood gas analysis is necessary, but not always available. The aim of the study was to evaluate the base excess (BE) of the sodium-chloride difference (BE = Na-Cl-34 mmol/l) as a screening parameter for hyperchloremic metabolic acidosis.

Nageotte nodules in human DRG reveal neurodegeneration in painful diabetic neuropathy.

Diabetic neuropathy is frequently accompanied by pain and loss of sensation attributed to axonal dieback. We recovered dorsal root ganglia (DRGs) from 90 organ donors, 19 of whom had medical indices for diabetic painful neuropathy (DPN). Nageotte nodules, dead sensory neurons engulfed by non-neuronal cells, were abundant in DPN DRGs and accounted for 25% of all neurons.