Publications by authors named "G A Deveber"
Objective: To assess variability among data elements collected among existing neonatal hypoxic-ischemic encephalopathy (HIE) data registries worldwide and to determine the need for future harmonization of standard common data elements.
Study Design: This was a cross-sectional study of data elements collected from current or recently employed HIE registry data forms. Registries were identified by literature search and email inquiries to investigators worldwide.
Article Synopsis
- Motor impairments are common after childhood arterial ischemic stroke (C-AIS), affecting the understanding of how these impairments relate to intellectual abilities in children.
- A study of 34 children with C-AIS found that motor functioning in early recovery significantly correlates with various intellectual skills, including verbal and perceptual reasoning abilities.
- The results suggest that early motor deficits may influence intellectual development due to neuroplastic changes after injury, while motor functions assessed closer to testing reflect recovery and improvement potentially aided by interventions.
Article Synopsis
- The study investigates how the age at which a pediatric patient suffers an arterial ischemic stroke affects their long-term neurological outcomes and how this interacts with the location and extent of the brain injury.
- Conducted at the Hospital for Sick Children in Toronto, the research followed 285 children diagnosed with strokes from 1996 to 2016 and used various models to analyze outcomes based on age groups and infarct characteristics.
- Results show that older children have worse outcomes, particularly when the stroke affects multiple areas of the brain, with significant differences in outcomes noted between age-at-stroke and specific brain regions impacted.
Background: The gold standard for evaluation of the severity of moyamoya vasculopathy is the Suzuki grade determined with cerebral catheter angiography (CA). With greater use of magnetic resonance angiography (MRA) it is important to understand if MRA is truly comparable to CA.
Methods: Children with moyamoya were evaluated using the Suzuki score for CA and the modified MRA six-stage Suzuki score to describe the angiographic findings in moyamoya from initial narrowing of the distal internal carotid artery to the "puff of smoke" appearance of the lenticulostriate collaterals and finally to the disappearance of this network of collaterals.
Background: Moyamoya is a progressive, non-atherosclerotic cerebral arteriopathy that may present in childhood and currently has no cure. Early diagnosis is critical to prevent a lifelong risk of neurological morbidity. Blood-oxygen-level-dependent (BOLD) MRI cerebrovascular reactivity (CVR) imaging provides a non-invasive, in vivo measure of autoregulatory capacity and cerebrovascular reserve.
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