Seasonal variations in the levels of glyphosate in soil, water and crops from three farm settlements in Oyo state, Nigeria.

This study investigated the concentration of glyphosate in water (groundwater and surface), soil (top and sub) on cassava and maize farms within 3 farm settlements (Akufo, Ilora and Otiri Ipapo) from Ido, Oyo and Iseyin Local Government Areas of Oyo state, Nigeria. Samples of Top and sub soil were taken from the farms while water was collected from wells (groundwater) and streams (surface water) around each farm settlement using standard methods. Crops (cassava and Maize) samples were collected from each of the selected farm after harvest.

Pre-puberty cannabichromene exposure modulates reproductive function via alteration of spermatogenesis, steroidogenesis, and eNOS pathway metabolites.

Background: Cannabis and cannabinoids affect almost every system of the body and exert systemic effects such as alterations in memory and cognitive functions, neurotransmission impediment, as well as obstruction of endocrine and reproductive system functions. Reproduction is a complicated phenomenon that integrates biological, psychological and behavioural aspects, hence susceptible to intracellular and extracellular modulations by numerous chemicals and toxicants like cannabis.

Aim: The effects of early-life exposure to cannabis on reproductive function biomarkers and genes were investigated in male and female Wistar rats in this study.

Implications of atrazine concentrations in drinking water from Ijebu-North, Southwest Nigeria on the hypothalamic-pituitary-adrenal axis.

There is an increasing overdependence and use of atrazine herbicide for the control of pre-and post-emergence broad leaf weeds on maize farms in rural agricultural communities in Nigeria. We carried out a survey of atrazine residue in 69 hand-dug wells (HDW), 40 boreholes (BH) and 4 streams from all the 6 communities (Awa, Mamu, Ijebu-Igbo, Ago-Iwoye, Oru and Ilaporu) in Ijebu North Local Government Area, Southwest Nigeria. The effect of the highest concentration of atrazine detected in the water from each of the communities on the hypothalamic-pituitary-adrenal (HPA) axis of albino rats was investigated.

Human health risks and hepatotoxicity associated with exposure to atrazine surveyed in drinking water from Ijebu-North, Southwest, Nigeria.

No recognized study has been conducted in rural agricultural areas in Nigeria to monitor atrazine in drinking water and its potential health implications. Here, a total of 69 hand-dug wells (HDW), 40 boreholes (BH), and 4 streams were collected from the six (6) communities in Ijebu-North Local Government Area, Southwest Nigeria and analyzed for atrazine residue using gas chromatography-mass spectrometry (GC-MS). Values of atrazine obtained were further used to evaluate the non-carcinogenic risk associated with ingestion and dermal routes in children and adults using the standard US EPA protocols.

Outcome of the first survey of atrazine in drinking water from Ijebu-North, South-West, Nigeria: Human health risk and neurotoxicological implications.

No recognised study has been conducted to monitor atrazine residue in drinking water from rural agricultural areas in Nigeria and its potential health implications. In this ecotoxicological study, we monitored atrazine residue in 69 hand-dug wells (HDW), 40 boreholes (BH) and 4 major streams from all the 6 communities (Ago-Iwoye, Ijebu-Igbo, Oru, Awa, Ilaporu and Mamu) in Ijebu North Local Government Area, Southwest Nigeria. Values of atrazine obtained were further used to evaluate the non-carcinogenic risk associated with ingestion and dermal contact in adults and children as well as neurotoxicity assessment.