Publications by authors named "G A Brockmann"
The global spread of Oriental Horses in the past 1,500 years through the lens of the Y chromosome.
Proc Natl Acad Sci U S A
December 2024
Article Synopsis
- Horses have been shaped by human needs through selective breeding, leading to a very uniform male-specific portion of the Y chromosome (MSY) across modern breeds.
- The study analyzed 1,517 males from 189 horse breeds, revealing the significant influence of Oriental stallions, especially Arabian and English Thoroughbred, over the past few centuries.
- Additionally, the research uncovered two major historical waves of horse dissemination, including the "Spanish influence" from the Iberian Peninsula and the spread during the Ottoman Empire's expansion, highlighting the complex ancestry of modern horses.
The COVID-19 pandemic demonstrated that reliable risk assessment of venues is still challenging and resulted in the indiscriminate closure of many venues worldwide. Therefore, this study used an experimental, numerical and analytical approach to investigate the airborne transmission risk potential of differently ventilated, sized and shaped venues. The data were used to assess the magnitude of effect of various mitigation measures and to develop recommendations.
View Article and Find Full Text PDFMastitis in cattle is often caused by microorganism infections in the udder. The three most common pathogens are esculin-positive streptococci (SC+), coagulase-negative staphylococci (CNS), and Escherichia coli (E. coli).
View Article and Find Full Text PDFThe beneficial effects of feeding probiotic DSM 32315 (BS) and CECT 5940 (BV) to chickens are well-documented, with potential immune modulation as a key mechanism. In this study, we investigated the direct interactions of chicken peripheral blood mononuclear cells (PBMCs) with BS or BV through whole transcriptome profiling and cytokine array analysis. Transcriptome profiling revealed 20 significantly differentially expressed genes (DEGs) in response to both treatments, with twelve DEGs identified in BS-treated PBMCs and eight in BV-treated PBMCs.
View Article and Find Full Text PDFThe Berlin Fat Mouse Inbred line (BFMI) is a model for obesity and metabolic syndrome. The sublines BFMI861-S1 and BFMI861-S2 differ in weight despite high genetic similarity and a shared obesity-related locus. This study focused on identifying additional body weight quantitative trait loci (QTLs) by analyzing weekly weight measurements in a male population of the advanced intercross line BFMI861-S1 x BFMI861-S2.
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