[Therapeutic-prophylactic milk products with a new immunocorrector of natural origin].

Authors had received and investigated on experiment milk medical and prophylactic products (milk and kefir) with addition peptide, obtained from nervous tissue of squids. It has been established that addition of gangliin to the milk and kefir causes stimulation cellular and humoral factors of immunity answer at laboratory animals. Medical and prophylactic milk products with gangliin return to the normal state reduced immunity indexes of the mice with experimental immunodeficits.

[Effectiveness of peroral application of a new immunocorrective agent of natural origin].

Data on peroral application of new peptide origin immunocorrector from nervous tissue of hydrobionts are cited. It has been established that immunological gangliin activity, perorally introduced, is close to that being applied parenterally. This drug comprises a soft immunocorrector that is expressed by humoral and cellular factor strengthening of immunity, increasing induces of phagocynosis of PMNC and sells SMPh.

[Effect of a peptide from the mollusk optical ganglia on macrophage functional activity].

Gangliin (tinrostim), a novel peptide isolated from the nervous tissue of the food mollusks, was investigated with respect to its effect on the cells of the system of the mononuclear phagocytes. It was shown to have a high protective action in some experimental infections. One of the main mechanisms of the gangliin action was the increase of the functional activity of the cells of the system of the mononuclear phagocytes.

[Immunoactive peptide obtained from the optical ganglia of squid].

The data on the effect of a peptide from the squid optic ganglia named gangliin on some parameters of animal natural resistance are presented. It was shown that the prophylactic use of the peptide in mice 24 hours before their contamination with the lethal dose of E. coli protected 40 to 60 per cent of the animals from death.