Publications by authors named "G A Banat"
Article Synopsis
- Alpha-thalassemia X-linked intellectual disability syndrome (ATRX) is a genetic disorder caused by mutations in the ATRX gene, leading to distinct physical features, alpha thalassemia, intellectual disability, and epilepsy in about 30% of cases.
- A case study of a 36-year-old patient highlights severe intellectual disability and epilepsy linked to a specific pathogenic variant in the ATRX gene.
- This report contributes to existing knowledge by documenting the simultaneous occurrence of seizure-related and non-seizure related apnea, enhancing the understanding of respiratory issues in ATRX syndrome.
Background: Own studies from the years 2013 and 2014 had shown that patients in hospital or inhabitants of nursing home get transferred even in their last, terminal phase of life.
Method: In order to describe such transfers, a 27-item questionnaire was developed in 2016. This was addressed to employees from hospitals and nursing homes.
Recent studies indicate that the abnormal microenvironment of tumors may play a critical role in carcinogenesis, including lung cancer. We comprehensively assessed the number of stromal cells, especially immune/inflammatory cells, in lung cancer and evaluated their infiltration in cancers of different stages, types and metastatic characteristics potential. Immunohistochemical analysis of lung cancer tissue arrays containing normal and lung cancer sections was performed.
View Article and Find Full Text PDFIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal lung disease with no known etiology and treatment options. The hallmarks of the histopathology, which is characteristic of usual interstitial pneumonia (UIP) pattern, include interstitial fibrosis, honeycomb changes and fibroblast foci that develop owing to fibroblast proliferation and excessive matrix deposition. Although the complete pathomechanism is not yet understood, several molecular culprits, including transforming growth factor (TGF)-β, Angiotensin (Ang) II, endothelin (ET)-1, matrix metalloproteinases (MMPs) and cytokines have been identified.
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