PRESIUS, Predictive value of sonographic functional urethral length and urethral closure angle for the diagnosis of stress urinary incontinence.

Introduction: Numerous anatomical theories have been developed to explain women stress urinary incontinence (SUI) and improve its management. The transperineal ultrasound is an efficient and non-invasive exam that perfectly studies the bladder neck movement and the urethral anatomy. The measurement of the static portion of the distal urethral length, considered as the functional urethral length (FUL), and of the posterior urethral closure angle (PUCA) have not been studied before and could be of interest.

Ciprofloxacin hydrochloride-loaded ocular silk fibroin liposomes: Formulation, characterisation, cytotoxicity, and antimicrobial activity.

Ocular drugs have low absorption because of the unique environment in the eye, making ocular drugs one of the most challenging pharmaceutical initiatives. Liposomes have shown to be a promising ocular drug delivery system over the years because of enhanced drug absorption, biocompatibility, and biodegradability. Utilising a mucoadhesive material alongside liposomes could be a promising strategy to increase the therapeutic efficacy of ocular drugs.

Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes.

The sinoatrial node regulates the heart rate throughout life. Failure of this primary pacemaker results in life-threatening, slow heart rhythm. Despite its critical function, the cellular and molecular composition of the human sinoatrial node is not resolved.

The commitment of the human cell atlas to humanity.

The Human Cell Atlas (HCA) is a global partnership "to create comprehensive reference maps of all human cells-the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring, and treating disease." ( https://www.humancellatlas.

Assessment of an original dental autotransplantation technique: A retrospective study and proposal of a method.

Background: Successful tooth autotransplantation (TAT) requires preservation of the periodontal ligament (PDL) on donor teeth and good vascularization of the recipient site to ensure maintenance of alveolar bone volume through physiological stimulation of PDL. This retrospective study aims to evaluate the survival and success rate of a two-step procedure that uses dual periodontal stimulation and a 3D replica of the transplanted tooth to promote ligament repair and prevent ankylosis and root resorption.

Material And Methods: All consecutive patients followed at the dental center of Rennes and having undergone a TAT in two surgical stages with double periodontal stimulation and the use of a 3D replica of the transplanted tooth between 2017 and 2022 were invited for follow-up clinical and radiographic examination.