Publications by authors named "G A B Buga"
Objectives: To assess the accuracy and utility of transabdominal sonographic paraumbilical and suprapubic sliding signs in predicting intra-abdominal adhesions in women undergoing repeat Cesarean section (CS), and to investigate the association of repeat CS with short-term maternal and neonatal outcomes.
Methods: This was a prospective observational study of pregnant women with a history of CS who were scheduled for third-trimester elective or emergency CS at a tertiary referral and teaching hospital between July 2021 and June 2022. In order to evaluate the role of transabdominal sonographic paraumbilical and suprapubic sliding signs in the prediction of intra-abdominal adhesions, participants underwent a high-resolution transabdominal ultrasound scan prior to repeat CS.
Arterial stiffness in women previously with preeclampsia from a semi-rural region of South Africa.
Clin Exp Hypertens
January 2019
Women with pre-eclampsia have an increased risk of cardiovascular disease later in life. The aim of the study was to establish the presence and pattern of arterial stiffness in women previously with pre-eclampsia from a semi-rural region of South Africa. This was a prospective longitudinal study which involved 36 previously pre-eclamptic women and 86 non-pregnant controls (NPC) who had a past history of non-complicated pregnancy.
View Article and Find Full Text PDFBackground: Preeclampsia is associated with arterial stiffness and endothelial dysfunction. The pathophysiology of arterial tone in preeclampsia has not been well described in rural African population, where the incidence is higher.
Objective: The aim of the study was to compare arterial tone of preeclamptic with pregnant normotensive women assessed with noninvasive techniques, using applanation tonometry with SphygmoCor.
Angiogenic imbalance as a contributor to the pathophysiology of preeclampsia among black African women.
J Matern Fetal Neonatal Med
June 2017
Article Synopsis
- The study investigates the roles of angiogenic factors sFLT1 and PlGF in preeclampsia among black African women, filling a gap in research for this demographic.
- Conducted at Mthatha hospital in South Africa, the research compares blood samples from 51 women with preeclampsia to 82 women with normal pregnancies, focusing on the levels of sFLT1 and PlGF.
- Findings reveal that women with preeclampsia have lower PlGF and higher sFLT1 levels, indicating an altered angiogenic balance that may contribute to the condition's development, similar to observations in other populations.
Objectives: The EndoPAT method has been used as a non-invasive method for assessing endothelial function in several non-pregnant populations. We investigated its possible use in assessing endothelial dysfunction in pre-eclampsia.
Methods: Two hundred and fifteen participants were recruited and grouped as pre-eclamptic cases (105) and normotensive controls (110).