Publications by authors named "Fuzuli Tugrul"
Article Synopsis
- The study aimed to evaluate the effectiveness of stereotactic body radiotherapy (SBRT) on patients with oligometastatic colorectal cancer (CRC) and its impact on survival and local control rates.
- A total of 388 patients with up to 5 metastatic lesions were analyzed, showing that most had previously undergone surgery and had limited organ involvement, with median follow-up of about 30.7 months.
- Results indicated that higher SBRT doses (≥100 Gy) significantly improved local control, progression-free survival, and overall survival rates, highlighting SBRT as a promising treatment for metastatic CRC.
Investigating the levels of depression, anxiety, sexual disorders, and other influencing factors in breast cancer patients: Turkish radiation oncology integrative group study (12-05).
Medicine (Baltimore)
November 2023
Article Synopsis
- Breast cancer patients often feel very scared and sad because of their illness and its treatments, which can affect their mental health.
- A study looked at how many patients felt depressed, anxious, and had sexual problems after surgery, finding that about 1 in 3 felt really sad and about 1 in 5 were very anxious.
- The study showed that some reasons for these feelings included the type of surgery they had, not getting enough information about side effects, and other health issues, highlighting the need for better support for patients' mental and emotional health.
Purpose: We aimed to investigate the patterns of radiotherapy (RT) care in cases of benign diseases in Turkey.
Methods: A questionnaire survey was sent to all radiation oncology (RO) departments in Turkey. The number of patients treated for benign disease between 2015 and 2020 was requested.
A biospectroscopic approach toward colorectal cancer diagnosis from bodily fluid samples via ATR-MIR spectroscopy combined with multivariate data analysis.
Spectrochim Acta A Mol Biomol Spectrosc
January 2024
In this study, a biospectroscopic approach was reported for the detection of spectral changes and biomarkers for the diagnosis of colorectal cancer (CC) cases from different bodily fluids (blood plasma, blood serum, saliva and colonoscopy disinfection/wash fluids) by using attenuated total reflection-mid infrared (ATR-MIR) spectroscopy. To recognize the molecular level changes in the spectral characteristics of CC and their healthy/control (CH) groups, different multivariate data analyses (HCA, LDA, PCA and SIMCA) were successfully performed over the data of ATR-MIR spectroscopy. Two hundred specimens were characterized in detail over the data of spectral regions (4000-650 cm and regions V-XXII).
View Article and Find Full Text PDFBackground: Long noncoding RNAs increase the overexpression of oncogenes. Cancer development and metastasis of cancer may occur as a result of overexpression of oncogenes. Polymorphisms in the genes (such as HOTAIR, etc.
View Article and Find Full Text PDFA rapid diagnostic approach for gastric and colon cancers via Fourier transform mid-infrared spectroscopy coupled with chemometrics from paraffin-embedded tissues.
Spectrochim Acta A Mol Biomol Spectrosc
February 2022
This paper describes the feasibility of Attenuated total reflection-Fourier transform mid-infrared (ATR-MIR) spectroscopy method coupled with chemometrics for the rapid diagnostic approach and screening spectral changes for gastric and colon cancers from paraffin-embedded tissues. A total number of 82 tissue samples were analyzed by a simple ATR-MIR method combined with PCA, HCA, SIMCA and LDA methodologies. Spectral analyses showed significant differences for the molecular contents particularly about the lipid, nucleic acid, protein and other biomolecules in the samples of gastric cancer (GC) and colon cancer (CC) groups from their control/healthy groups.
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