Anti-hypertrophic effect of synovium-derived stromal cells on costal chondrocytes promotes cartilage repairs.

Background: Costal chondrocytes (CCs), as a promising donor cell source for cell-based therapy for cartilage repair, have strong tendency of hypertrophy and calcification, which limited CCs from further application in cartilage regenerative medicine. Synovium-derived stromal cells (SDSCs), have shown their beneficial effect for chondrocytes to maintain phenotype. This study aims to investigate whether SDSCs could help CCs to maintain chondrogenic phenotype and suppress hypertrophic differentiation in cartilage repairs.

[Surgical techniques and effectiveness of volar locking plates for senile delayed distal radius fractures].

Objective: To investigate the surgical technique and effectiveness of volar locking plates for senile delayed distal radius fractures.

Methods: Between October 2014 and September 2015, 25 cases of delayed distal radius fractures were treated by volar locking plates. There were 3 males and 22 females with an average age of 73 years (range, 65-87 years).