Knowledge, attitude, and practice toward nonsteroidal anti-inflammatory drugs among osteoarthritis patients: a cross-sectional study.

Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are common drugs in patients with osteoarthritis (OA). NSAIDs are generally used at home by patients, without supervision, requiring proper knowledge and attitudes for correct practice. This study investigated the knowledge, attitude, and practice (KAP) of patients with OA toward NSAIDs.

Research on shared control of robots based on hybrid brain-computer interface.

Background: With the arrival of the new generation of artificial intelligence wave, new human-robot interaction technologies continue to emerge. Brain-computer interface (BCI) offers a pathway for state monitoring and interaction control between human and robot. However, the unstable mental state reduce the accuracy of human brain intent decoding, and consequently affects the precision of BCI control.

A Modular Event-Triggered Containment Control Scheme for Nonlinear Heterogeneous Multiagent Systems With Unknown Leaders.

This article addresses the containment control problem in multiagent systems with nonlinear heterogeneous followers and multiple unknown leaders whose dynamics are exclusively known to their neighbors. The primary goal is to ensure the convergence of each follower to the dynamic convex hull spanned by the leaders under the constraints of limited communication resources. To achieve this, this article introduces a modular event-triggered containment control scheme with three modules.

Biogenic preparation of copper oxide nanoparticles using table olive: Catalytic reduction, cytotoxicity, and burn wound healing activities.

Green strategy for the preparation of copper oxide nanoparticles (CuO NPs) using table olive has been researched in the present work. Some characterization assays viz., transmission electron microscopy (TEM), X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy-dispersive X-ray (EDX) was used for evaluation of the crystal structure, size and morphology of the manufactured NPs.

Pathogenicity and epidemiological survey of fowl adenovirus in Shandong Province from 2021 to 2022.

In recent years, the poultry industry had been markedly affected by adenoviral diseases such as hydropericardium syndrome and inclusion body hepatitis caused by fowl adenovirus (FAdV), which have become increasingly prevalent in China. Shandong Province, China, is an important area for poultry breeding where various complex and diverse FAdV serotypes were isolated. However, the dominant strains and their pathogenic characteristics are not yet reported.

Composite Learning Adaptive Tracking Control for Full-State Constrained Multiagent Systems Without Using the Feasibility Condition.

This article proposes a distributed consensus tracking controller for a class of nonlinear multiagent systems under a directed graph, in which all agents are subject to time-varying asymmetric full-state constraints, internal uncertainties, and external disturbances. The feasibility condition generally required in the existing constrained control is removed by using the proposed nonlinear mapping function (NMF)-based state reconstruction technology, and the Lipschitz condition usually needed in the consensus tracking is also canceled based on the adaptive command-filtered backstepping framework. The composite learning of the neural network-based function approximator (NN-FAP) and the finite-time smooth disturbance observer (DOB) provides a novel scheme for handling internal and external uncertainties simultaneously.

Distributed Adaptive Fault-Tolerant Control for Multiagent Systems via Virtual-Actuator-Based Reconfiguration.

This article aims to develop a virtual-actuator-based control scheme for the consensus tracking problem of multiagent systems (MASs) against actuator faults and mismatched disturbances. The proposed scheme has a double-layer structure. In the cyber layer, the nominal controller is designed with neighboring information for the fault-free case.

A Mathematical Model of Surfactant Spontaneous Imbibition in a Tight Oil Matrix with Diffusion and Adsorption.

Surfactants can significantly improve the oil recovery of spontaneous imbibition (SI) in unconventional oil reservoirs, but mathematical modeling of surfactant SI for displacing oil in a tight matrix is challenging because of its complex mechanism. Considering the mechanisms of surfactant diffusion and adsorption, the flow equation for the SI of surfactant solution into an oil-saturated capillary is derived, and the dynamic capillary pressure and surfactant concentration during the SI process are characterized. Then, based on the pore size distribution of the pores in a tight matrix, a core-scale mathematical model for SI of surfactant solution into an oil-saturated tight matrix is developed and validated with experimental data from the literature.

Protective effect of Corynoline on the CFA induced Rheumatoid arthritis via attenuation of oxidative and inflammatory mediators.

Rheumatoid arthritis (RA) is a long-standing and growing autoimmune disease. Therefore, the present study was intended to investigate the effect of Corynoline (COR) on CFA induced rheumatoid arthritis in a rat model. Results suggested that COR causes significant reduction in paw swelling, edema, arthritis score, thymus and spleen indexes and neutrophil infiltration (p < 0.

Fully distributed containment control for second-order multi-agent systems with communication delay.

In this paper, fully distributed containment control problems of multi-agent systems with double-integrator dynamics are investigated under directed topologies. For the cases with and without communication delay, two new fully distributed control protocols are designed, which do not need any global information of the communication topology graph. Necessary and sufficient conditions are obtained to ensure the solvability of the considered containment control problems.

Containment Control for General Second-Order Multiagent Systems With Switched Dynamics.

This paper investigates the distributed containment control problem for a class of general second-order multiagent systems with switched dynamics, which is composed of a continuous-time (CT) subsystem and a discrete-time (DT) subsystem. For this switched multiagent system under fixed directed topology, a distributed containment control protocol is proposed for each follower based on the relative local measurements of neighboring followers and leaders. Some necessary and sufficient conditions are derived under the condition that the network topology contains a directed spanning forest, and these conditions ensure that the general second-order containment control problem can be solved under arbitrary CT-DT switching.

Cysticercosis in Shandong Province, Eastern China.

We analyzed demographic and clinical data and estimated the incidence of cysticercosis in Shandong Province, China, during 1975-2014. Our analyses showed that a cysticercosis-endemic area is present in Shandong Province, especially in its western regions. Improved surveillance and control are needed to address the elevated risk for cysticercosis in this region.

Regulation of type II collagen, matrix metalloproteinase-13 and cell proliferation by interleukin-1β is mediated by curcumin via inhibition of NF-κB signaling in rat chondrocytes.

Curcumin possesses strong anti-inflammatory, anti-rheumatoid and anti-oxidative activities, and has the potential to inhibit nuclear factor‑κB (NF‑κB) signaling. Cartilage damage in osteoarthritis (OA) is largely mediated by interleukin-1β (IL-1β) via activation of various transcription factors, including NF‑κB and activator protein‑1. The aim of the present study was to determine whether IL‑1β induces matrix metalloproteinase-13 (MMP-13) expression and inhibits type II collagen expression, as well as to examine whether cell proliferation may be inhibited by curcumin through the inhibition of NF‑κB signaling.

8.5 W mode-locked Yb:Lu1.5Y1.5Al5O12 laser with master oscillator power amplifiers.

We report on a diode-pumped passively mode-locked Yb:Lu(1.5)Y(1.5)Al(5)O(12) (Yb:LuYAG) laser for the first time to our knowledge.

[Therapeutic effect of 138 imported falciparum malaria patients].

Objectives: To summarize the clinical characteristics of imported falciparum malaria patients and the treatment, so as to provide the evidences for improving the diagnosis and treatment of the disease.

Methods: A total of 138 imported falciparum malaria patients who received the treatment in Shandong Institute of Parasitic Diseases from January 2007 to February 2013 were adopted as the observation subjects, and their clinical data were collected and analyzed.

Results: All the 138 patients were back from African countries.

A reduction technique of arthroplasty without subtrochanteric femoral shortening osteotomy for the treatment of developmental high dislocation of hip: a case series of 28 hips.

In total hip arthroplasty for the treatment of developmental dysplasia of the hip (DDH) with high hip dislocation, it can be technically challenging to locate the true acetabulum and restore limb length without subtrochantric femoral shortening osteotomy. We explored and described total hip arthroplasty without subtrochanteric femoral shortening osteotomy in 28 hips with Crowe type III and IV dislocation by intravenous injection of rocuronium at 0.9mg/kg 1minute before reduction and hip reduction combined with continuous strong traction of the affected limb with patients in a position with hip and knee flexion.