Background: Most related research focuses on a single variable of verbal and nonverbal behaviors independently without considering their associations. Therefore, it is important to understand subclinical depression in the entire population.
Aims: This study investigated the cross-modal co-occurrence of nonverbal behavior with vocal emotions, prosody, and content words in individuals with subclinical depression.
In the paper, we synthesized amorphous NiCoB nanoparticles by a simple chemical reduction method and employed them as high-activity catalysts to considerably improve the hydrogen storage properties of MgH. The MgH-NiCoB composite quickly absorbed 3.6 wt % H at a low temperature of 85 °C and released 5.
View Article and Find Full Text PDFHerein, an active positive electrode material, LiCoO nanosheets, was synthesized a two-step method, which demonstrated a remarkable catalytic effect for the hydrogen storage property of MgH. Incorporated with LiCoO nanosheets, MgH started to release hydrogen at 180 °C and a desorption content as high as 5.5 wt% H was attained within 60 min at 250 °C.
View Article and Find Full Text PDFHyperactivation of glutamatergic N-methyl-D-aspartate (NMDA) receptors has been implicated in the excitotoxicity and pathophysiology of Parkinson's disease (PD). NMDA receptor blockers have been used clinically to treat dementia, but their efficacy is controversial. Modulation of NMDA receptors might improve neuroinflammation and cognitive deficits in PD.
View Article and Find Full Text PDFHyperactivity of the glutamatergic system is involved in excitotoxicity and neurodegeneration in Parkinson's disease (PD). Metabotropic glutamate receptor subtype 5 (mGluR5) modulates glutamatergic transmission and thus has been proposed as a potential target for neuroprotective drugs. The aim of this study was to determine the effects of 2-methyl-6-(phenylethynyl)-pyridine (MPEP), an mGluR5 antagonist, on working memory, object recognition, and neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD rat model.
View Article and Find Full Text PDFSeveral years after the diagnosis of Parkinson's disease (PD), 20-30% of PD patients develop dementia, known as Parkinson's disease dementia (PDD), the features of which include impairment of short-term memory and recognition function. Hyperactivation of the glutamatergic system is implicated in the neurodegeneration seen in PD. The aim of this study was to determine the effects of MK-801, an N-methyl-d-aspartate (NMDA) receptor antagonist, on short-term memory and object recognition in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD rat animal model.
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