Integrated Acetabular Prosthesis Versus Bone Grafting in Total Hip Arthroplasty for Crowe Type II and III Hip Dysplasia: A Retrospective Case-Control Study.

Objective: Many methods of acetabular reconstruction with total hip arthroplasty (THA) for Crowe type II and III adult developmental dysplasia of the hip (DDH) acetabular bone defect have been implemented clinically. However, there was no study comparing the results of integrated acetabular prosthesis (IAP) with bone grafting (BG). This study aims to investigate the efficacy of IAP and BG for acetabular reconstruction in Crowe type II and III DDH.

Principles and clinical applications of transcutaneous laser-assisted drug delivery: A narrative review.

Introduction: Transcutaneous laser-assisted drug delivery (LADD) is recognized as a developing therapy for skin disorders.

Method: Current literature was reviewed to summarize current applications for LADD.

Discussion: 12 clinical applications for this therapy are currently reported.

Biomechanical analysis and clinical observation of 3D-printed acetabular prosthesis for the acetabular reconstruction of total hip arthroplasty in Crowe III hip dysplasia.

This study aimed to evaluate the biomechanical effectiveness of 3D-printed integrated acetabular prosthesis (IAP) and modular acetabular prosthesis (MAP) in reconstructing the acetabulum for patients with Crowe III developmental dysplasia of the hip (DDH). The results of this study can provide a theoretical foundation for the treatment of Crowe III DDH in total hip arthroplasty (THA). Finite element (FE) analysis models were created to reconstruct Crowe III DDH acetabular defects using IAP and MAP.

Finite element analysis of biomechanical effects of mineralized collagen modified bone cement on adjacent vertebral body after vertebroplasty.

To investigate whether mineralized collagen modified polymethyl methacrylate (MC-PMMA) bone cement impacts the implanted vertebral body and adjacent segments and the feasibility of biomechanical properties compared with common bone cement in the treatment of osteoporotic vertebral compression fractures (OVCF). A healthy volunteer was selected to perform a three-dimensional reconstruction of the T11-L1 vertebral body to establish the corresponding finite element model of the spine, and the changes in the stress distribution of different types of cement were biomechanically analyzed in groups by applying quantitative loads. The stress distribution of the T11-L1 vertebral body was similar between the two bone types of cement under various stress conditions.

[Biomechanical research progress of common acetabular reconstruction techniques for Crowe type and developmental dysplasia of the hip].

Objective: To summarize the characteristics and biomechanical research progress of common acetabular reconstruction techniques in patients with Crowe type Ⅱ and Ⅲ developmental dysplasia of the hip (DDH) undergoing total hip arthroplasty (THA), and provide references for selecting appropriate acetabular reconstruction techniques for clinical treatment of Crowe type Ⅱ and Ⅲ DDH.

Methods: The domestic and foreign relevant literature on biomechanics of acetabular reconstruction with Crowe type Ⅱ and Ⅲ DDH was reviewed, and the research progress was summarized.

Results: At present, there are many acetabular reconstruction techniques in Crowe type Ⅱ and Ⅲ DDH patients undergoing THA, with their own characteristics due to structural and biomechanical differences.

Biomechanical study of internal fixation methods for femoral neck fractures based on Pauwels angle.

To select the most appropriate internal fixation method based on the Pauwels angle, in order to provide a new concept for clinical accurate treatment of femoral neck fractures (FNFs). FNFs models of Pauwels ; ; ; were created respectively. For Pauwels ≤ , 1, 2 and 3 Cannulated Compression Screws (CCS) and Porous Tantalum Screws (PTS) were used to fix the fracture for the models.

Treatment of Acetabular Bone Defect in Revision of Total Hip Arthroplasty Using 3D Printed Tantalum Acetabular Augment.

Objective: The treatment of acetabular defects is one of the most difficult challenges of revision of total hip arthroplasty (RTHA), and tantalum is regarded as a promising bone substitute material. This study aims to investigate the effectiveness of 3D printed acetabular augment used in RTHA for the treatment of acetabular bone defect.

Methods: A retrospective analysis of the clinical data of seven patients who had undergone RTHA was carried out using 3D printed acetabular augment from January 2017 to December 2018.

[Research progress in biomechanics of common internal fixation for femoral neck fracture].

Objective: To summarize the characteristics and biomechanical research progress of common internal fixation for femoral neck fractures in recent years, so as to provide reference to clinical treatment of femoral neck fracture.

Methods: The domestic and foreign relevant literature on biomechanics of internal fixation of femoral neck fracture in recent years was reviewed, and the biomechanical research progress was summarized.

Results: Among the internal fixations currently used in the treatment of femoral neck fractures, three cannulated screws can provide sliding compression at the end of the fracture, but the shear resistance is weak, and the risk of long-term internal fixation failure is high; dynamic hip screw and proximal femoral locking plate have excellent angle stability and overall strength; medial buttress plate can transform vertical shear force into compressive stress to promote fracture healing and produce a certain anti-rotation effect; femoral neck system can support the fracture in multi-axial direction, with excellent anti-rotation and anti-shortening properties; and cephalomedullary nails have high overall strength and failure load.

Assessment of culturable airborne bacteria of indoor environments in classrooms, dormitories and dining hall at university: a case study in China.

University students' health may be adversely affected by exposure to indoor bacterial contaminants on their campuses. This study aims (1) to quantify culturable bacterial concentrations in three indoor environments at a university, (2) to investigate the influence of meteorological factors and gender, to assess the relationship between indoor and outdoor, and (3) to estimate the bacterial dose for university students in different indoor environments. Airborne bacteria samples were collected in 12 classrooms, in 12 living rooms and four bathrooms in two dormitory buildings, and in a dining hall.

Partial physicochemical properties and relative stability of polyhydroxylated dibenzofurans: theoretical and experimental study.

Polyhydroxylated dibenzofuran (PHODF) is an important degradation product of polychlorinated dibenzofuran (PCDF). Four types of hydrogen bonds (the one between a hydroxyl and the oxygen atom in the matrix, between hydroxyls at ortho positions, between the oxygen atom of hydroxyl at position 1 and the hydrogen atom of the matrix at position 9, and between hydroxyls at positions 1 and 9) exist in PHODFs. The energies of the hydrogen bonds were ascertained by comparing the two configurational isomers as approximately 8-11 kJ mol⁻¹, 16-21 kJ mol⁻¹, 5-8 kJ mol⁻¹ and 23-25 kJ mol⁻¹, respectively.

2D and 3D-QSBR study on biodegradation of phenol derivatives.

Eighteen phenol derivatives were optimized with density function theory (DFT) and comparative molecular similarity indices analysis (CoMSIA) respectively. Corresponding 2D and 3D descriptors were obtained to establish QSBR models. The biodegradation of them is mainly related to α and S (ө) according to the 2D QSBR, and influenced by the hydrophobicity and hydrogen bonding properties following the 3D QSBR.